AIMC Topic: Glycopeptides
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Ultradeep N-glycoproteome atlas of mouse reveals spatiotemporal signatures of brain aging and neurodegenerative diseases.
Nature communications
Jul 1, 2025
The current depth of site-specific N-glycoproteomics is insufficient to fully characterize glycosylation events in biological samples. Herein, we achieve an ultradeep and precision analysis of the N-glycoproteome of mouse tissues by integrating multi...
Prediction of glycopeptide fragment mass spectra by deep learning.
Nature communications
Mar 19, 2024
Deep learning has achieved a notable success in mass spectrometry-based proteomics and is now emerging in glycoproteomics. While various deep learning models can predict fragment mass spectra of peptides with good accuracy, they cannot cope with the ...
Newest perspectives of glycopeptide antibiotics: biosynthetic cascades, novel derivatives, and new appealing antimicrobial applications.
World journal of microbiology & biotechnology
Jan 3, 2023
Glycopeptide antibiotics (GPAs) are a family of non-ribosomal peptide natural products with polypeptide skeleton characteristics, which are considered the last resort for treating severe infections caused by multidrug-resistant Gram-positive pathogen...
Machine Learning Classifies Core and Outer Fucosylation of N-Glycoproteins Using Mass Spectrometry.
Scientific reports
Jan 15, 2020
Protein glycosylation is known to be involved in biological progresses such as cell recognition, growth, differentiation, and apoptosis. Fucosylation of glycoproteins plays an important role for structural stability and function of N-linked glycoprot...
Absolute quantitation of high abundant Fc-glycopeptides from human serum IgG-1.
Analytica chimica acta
Dec 18, 2019
Absolute quantitation of IgG-1 Fc-glycosylation, which is crucial for the clinical practice of glyco-biomarkers and quality control of biopharmaceuticals, has been hindered by the lack of glycopeptide standards. In this study, eleven high abundant Ig...
Vasopressin and its copilot copeptin in sepsis and septic shock.
Critical care medicine
Feb 1, 2009
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