Hypophosphatasia (HPP) is a rare genetic disorder mainly affecting bone and tooth mineralization in patients due to ALPL gene mutations. Understanding genotype-phenotype correlations in HPP remains challenging due to different severities and the dise...
Fodder crops are crops which are mainly grown as feed for livestocks and it consist of a variety of crops ranging from annual to perennial crops. Even with many crops involved, advance crop improvement practices are done less in these crops. With the...
In the context of global economic austerity in the post epidemic era, housing, as one of the basic human needs, has become particularly important for accurate prediction of house prices. BP neural network is widely used in prediction tasks, but their...
Applied and environmental microbiology
Sep 16, 2025
UNLABELLED: Microbial communities play a vital role in cadaver decomposition and serve as reliable tools for postmortem interval (PMI) estimation. However, current research focuses primarily on bacterial/fungal communities, though viruses-as Earth's ...
Targeting therapeutic nanoparticles to the brain poses a challenge due to the restrictive nature of the blood-brain barrier (BBB). Here we report the development of mRNA-loaded lipid nanoparticles (LNPs) functionalized with BBB-interacting small mole...
Journal of agricultural and food chemistry
Sep 16, 2025
Glabridin (GLA), a characteristic polyphenolic extracted from the renowned sweet plant L., demonstrates potent anticancer effects. This study aims to investigate the effects of GLA on triple-negative breast cancer (TNBC) and its underlying mechanisms...
Stroke remains a leading cause of disability due to the brain's limited ability to regenerate damaged neural circuits. Here, we show that local transplantation of iPSC-derived neural progenitor cells (NPCs) improves brain repair and long-term functio...
Mice are among the most prevalent animal models used in neuroscience, benefiting from the extensive physiological, imaging, and genetic tools available to study their brain. However, the development of novel and optimized behavioral paradigms for mic...
Closed-loop neural stimulation provides novel therapies for neurological diseases such as Parkinson's disease (PD), but it is not yet clear whether artificial intelligence (AI) techniques can tailor closed-loop stimulation to individual patients or i...
The absolute positioning accuracy of industrial robots is much lower than that of repetitive. In this paper, an error compensation algorithm for industrial robots is proposed, which included the kinematic parameter calibration based on the enhanced D...
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