AIMC Topic: Anti-HIV Agents

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Factors associated with viral suppression among HIV-positive Kenyan gay and bisexual men who have sex with men.

AIDS care
The UNAIDS 90-90-90 target has prioritized achieving high rates of viral suppression. We identified factors associated with viral suppression among HIV-positive gay, bisexual, and other men who have sex with men (GBMSM) in Kisumu, Kenya. HIV-positive...

Factors Associated with HIV Viral Suppression Among Transgender Women in Lima, Peru.

LGBT health
PURPOSE: Globally, transgender women (TGW) experience a high burden of adverse health outcomes, including a high prevalence of HIV and sexually transmitted infections (STIs) as well as psychiatric disorders and substance use disorders. To address gap...

Real World Patient-reported Outcomes in HIV-infected Adults Switching to EVIPLERA®, Because of a Previous Intolerance to cART. PRO-STR Study.

Current HIV research
BACKGROUND: To investigate the impact of switching from stable Combined Antiretroviral Therapy (cART) to single-tablet regimen (RPV/FTC/TDF=EVIPLERA® /COMPLERA®) on patient- reported outcomes in HIV-infected adults who cannot tolerate previous cART, ...

[Young women with HIV infection acquired by vertical transmission: Expectations of having uninfected children].

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia
INTRODUCTION: Pediatric antiretroviral therapy (ART), changed the prognosis of the disease, allowing young women infected by vertical transmission (TV) to be pregnant without risk for their fetus of acquiring this infection.

Virological and immunological outcomes to antiretroviral therapy in HIV-infected patients of an academic medical center in Chile.

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia
INTRODUCTION: Red Salud UC is an Academic health network where HIV-infected patients from the public and private health system are followed by a multidisplinary team.

Tackling the problem of HIV drug resistance.

Postepy biochemii
The virally-encoded HIV-1 protease is an effective target for antiviral drugs, however, treatment for HIV infections is limited by the prevalence of drug resistant viral mutants. In this review, we describe our three-pronged approach to analyze and c...

Computer-Aided Optimization of Combined Anti-Retroviral Therapy for HIV: New Drugs, New Drug Targets and Drug Resistance.

Current HIV research
BACKGROUND: Resistance to antiretroviral drugs is a complex and evolving area with relevant implications in the treatment of human immunodeficiency virus (HIV) infection. Several rules, algorithms and full-fledged computer programs have been develope...

Super Learner Analysis of Electronic Adherence Data Improves Viral Prediction and May Provide Strategies for Selective HIV RNA Monitoring.

Journal of acquired immune deficiency syndromes (1999)
OBJECTIVE: Regular HIV RNA testing for all HIV-positive patients on antiretroviral therapy (ART) is expensive and has low yield since most tests are undetectable. Selective testing of those at higher risk of failure may improve efficiency. We investi...

Control of HIV/AIDS infection system with drug dosages design via robust H(∞) fuzzy controller.

Bio-medical materials and engineering
The designing of H∞ fuzzy controller for HIV/AIDS infected dynamic system has been considered in this paper. With TS fuzzy model and LMIs approach, the proposed controller is obtained for such a system. A set of sufficient conditions of the H∞ contro...

Unsupervised Structure Detection in Biomedical Data.

IEEE/ACM transactions on computational biology and bioinformatics
A major challenge in computational biology is to find simple representations of high-dimensional data that best reveal the underlying structure. In this work, we present an intuitive and easy-to-implement method based on ranked neighborhood compariso...