AIMC Topic: Bacteria
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Waste to resource: Mining antimicrobial peptides in sludge from metagenomes using machine learning.
Environment international
Mar 11, 2024
The emergence of antibiotic-resistant bacteria poses a huge threat to the treatment of infections. Antimicrobial peptides are a class of short peptides that widely exist in organisms and are considered as potential substitutes for traditional antibio...
Chemical multiscale robotics for bacterial biofilm treatment.
Chemical Society reviews
Mar 4, 2024
A biofilm constitutes a bacterial community encased in a sticky matrix of extracellular polymeric substances. These intricate microbial communities adhere to various host surfaces such as hard and soft tissues as well as indwelling medical devices. T...
Investigation of bacterial DNA gyrase Inhibitor classification models and structural requirements utilizing multiple machine learning methods.
Molecular diversity
Feb 19, 2024
Infections from multidrug-resistant (MDR) bacteria have emerged as a paramount global health concern, and the therapeutic effectiveness of current treatments is swiftly diminishing. An urgent need exists to explore innovative strategies for counterin...
An atlas of protein homo-oligomerization across domains of life.
Cell
Feb 6, 2024
Protein structures are essential to understanding cellular processes in molecular detail. While advances in artificial intelligence revealed the tertiary structure of proteins at scale, their quaternary structure remains mostly unknown. We devise a s...
Deep Learning-Based Culture-Free Bacteria Detection in Urine Using Large-Volume Microscopy.
Biosensors
Feb 5, 2024
Bacterial infections, increasingly resistant to common antibiotics, pose a global health challenge. Traditional diagnostics often depend on slow cell culturing, leading to empirical treatments that accelerate antibiotic resistance. We present a novel...
antibacterial activity of antiretroviral drugs on key commensal bacteria from the human microbiota.
Frontiers in cellular and infection microbiology
Jan 8, 2024
INTRODUCTION: Antiretroviral therapy has improved life expectancy in HIV-infected patients. However, people living with HIV under antiretroviral therapy are at higher risks of developing chronic complications and acquiring multidrug resistant bacteri...
Characterization of extended-spectrum beta-lactamase and carbapenemase genes in bacteria from environment in Burkina Faso.
Journal of infection in developing countries
Dec 31, 2023
INTRODUCTION: This study aimed to characterize extended-spectrum beta-lactamase (ESBL) and carbapenemase genes in bacteria from the environment in Bobo-Dioulasso, Burkina Faso.
Machine learning identification of Pseudomonas aeruginosa strains from colony image data.
PLoS computational biology
Dec 13, 2023
When grown on agar surfaces, microbes can produce distinct multicellular spatial structures called colonies, which contain characteristic sizes, shapes, edges, textures, and degrees of opacity and color. For over one hundred years, researchers have u...
Autoencoder neural networks enable low dimensional structure analyses of microbial growth dynamics.
Nature communications
Dec 1, 2023
The ability to effectively represent microbiome dynamics is a crucial challenge in their quantitative analysis and engineering. By using autoencoder neural networks, we show that microbial growth dynamics can be compressed into low-dimensional repres...
Deep learning enhanced multiplex detection of viable foodborne pathogens in digital microfluidic chip.
Biosensors & bioelectronics
Nov 17, 2023
Culture plating is worldwide accepted as the gold standard for quantifying viable foodborne pathogens. However, it is time-consuming (1-2 days) and requires specialized laboratory and personnel. This study reported a deep learning enhanced digital mi...
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