AIMC Topic: Bacterial Proteins
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Use of Chou's 5-steps rule to predict the subcellular localization of gram-negative and gram-positive bacterial proteins by multi-label learning based on gene ontology annotation and profile alignment.
Journal of integrative bioinformatics
Jun 29, 2020
To date, many proteins generated by large-scale genome sequencing projects are still uncharacterized and subject to intensive investigations by both experimental and computational means. Knowledge of protein subcellular localization (SCL) is of key i...
Photosynthetic protein classification using genome neighborhood-based machine learning feature.
Scientific reports
Apr 28, 2020
Identification of novel photosynthetic proteins is important for understanding and improving photosynthetic efficiency. Synergistically, genome neighborhood can provide additional useful information to identify photosynthetic proteins. We, therefore,...
ACNNT3: Attention-CNN Framework for Prediction of Sequence-Based Bacterial Type III Secreted Effectors.
Computational and mathematical methods in medicine
Apr 3, 2020
The type III secretion system (T3SS) is a special protein delivery system in Gram-negative bacteria which delivers T3SS-secreted effectors (T3SEs) to host cells causing pathological changes. Numerous experiments have verified that T3SEs play importan...
Artificial Intelligence and Machine learning based prediction of resistant and susceptible mutations in Mycobacterium tuberculosis.
Scientific reports
Mar 26, 2020
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (M.tb), causes highest number of deaths globally for any bacterial disease necessitating novel diagnosis and treatment strategies. High-throughput sequencing methods genera...
Humans
Artificial Intelligence
Machine Learning
Polymorphism, Single Nucleotide
Bayes Theorem
Bacterial Proteins
Algorithms
Molecular Docking Simulation
Drug Resistance, Multiple, Bacterial
Mycobacterium tuberculosis
Genes, Bacterial
Genes, MDR
Mutation
Tuberculosis, Multidrug-Resistant
Molecular Dynamics Simulation
Enhanced Fermentable Sugar Production from Enteromorpha Polysaccharides by the Crude Enzymes of Vibrio sp. H11.
Journal of molecular microbiology and biotechnology
Mar 6, 2020
In recent years, large-scale outbreaks of the green alga Enteromorpha prolifera in China's offshore waters have posed a serious threat. This study aimed to improve Enteromorpha polysaccharide (EP) enzymatic sugar production using the hydrolase system...
High-level expression of Thermobifida fusca glucose isomerase for high fructose corn syrup biosynthesis.
Enzyme and microbial technology
Dec 13, 2019
Glucose isomerase (GIase), an efficient enzyme in the isomerization of d-glucose to d-fructose, has been widely used in food processing. In this study, an efficient expression system for a Thermobifida fusca GIase (GIase) in Escherichia coli was firs...
PSO-LocBact: A Consensus Method for Optimizing Multiple Classifier Results for Predicting the Subcellular Localization of Bacterial Proteins.
BioMed research international
Nov 19, 2019
Several computational approaches for predicting subcellular localization have been developed and proposed. These approaches provide diverse performance because of their different combinations of protein features, training datasets, training strategie...
Prediction of essential genes in prokaryote based on artificial neural network.
Genes & genomics
Nov 17, 2019
BACKGROUND: Rapid identification of new essential genes is necessary to understand biological mechanisms and identify potential targets for antimicrobial drugs. Many computational methods have been proposed.
Compositional model based on factorial evolution for realizing multi-task learning in bacterial virulent protein prediction.
Artificial intelligence in medicine
Nov 7, 2019
The ability of multitask learning promulgated its sovereignty in the machine learning field with the diversified application including but not limited to bioinformatics and pattern recognition. Bioinformatics provides a wide range of applications for...
Molecular mechanisms of antibiotic co-resistance among carbapenem resistant Acinetobacter baumannii.
Journal of infection in developing countries
Oct 31, 2019
INTRODUCTION: The spread of carbapenem-resistant Acinetobacter baumannii (CRAB) is difficult to control especially in the hospitals due to the successful mobilization and evolution of the genetic elements harboring the resistant determinants. The stu...
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