The discovery of peptide substrates for enzymes with exclusive, selective activities is a central goal in chemical biology. In this paper, we develop a hybrid computational and biochemical method to rapidly optimize peptides for specific, orthogonal ...
IEEE journal of biomedical and health informatics
Dec 6, 2018
Our goal is data-driven discovery of features for text simplification. In this paper, we investigate three types of lexical chains: exact, synonymous, and semantic. A lexical chain links semantically related words in a document. We examine their pote...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Dec 5, 2018
Conventional text classification models make a bag-of-words assumption reducing text into word occurrence counts per document. Recent algorithms such as word2vec are capable of learning semantic meaning and similarity between words in an entirely uns...
Neural networks : the official journal of the International Neural Network Society
Dec 3, 2018
In this study, an efficient stochastic gradient-free method, the ensemble neural networks (ENN), is developed. In the ENN, the optimization process relies on covariance matrices rather than derivatives. The covariance matrices are calculated by the e...
This paper addresses the localization of a gas emission source within a real-world human environment with a mobile robot. Our approach is based on an efficient and coherent system that fuses different sensor modalities (i.e., vision and chemical sens...
The impact of mining activities on the environment is vast. In this regard, many mines were operating well before the introduction of environmental law. This is particularly true of cinnabar mines, whose activity has declined for decades due to growi...
With the high cost of the research assessment exercises in the UK, many have called for simpler and less time-consuming alternatives. In this work, we gathered publicly available REF data, combined them with library-subscribed data, and used machine ...
International journal of environmental research and public health
Nov 23, 2018
In order to quantitatively study the effect of environmental protection in China since the twenty-first century and the environmental pollution projected for the next ten years (under the model of extensive economic development), this paper establish...
OBJECTIVES: Finding recent clinical studies that warrant changes in clinical practice ("high impact" clinical studies) in a timely manner is very challenging. We investigated a machine learning approach to find recent studies with high clinical impac...
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