Biomaterials
Feb 20, 2023
Osteoporosis is caused by the disruption in homeostasis between bone formation and bone resorption. Conventional management of osteoporosis involves systematic drug administration and hormonal therapy. These treatment strategies have limited curative...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Feb 19, 2023
Three-dimensional (3D) bioprinting technology offers great potential in the treatment of tissue and organ damage. Conventional approaches generally rely on a large form factor desktop bioprinter to create in vitro 3D living constructs before introduc...
Advanced materials (Deerfield Beach, Fla.)
Dec 29, 2022
With the flourishing development of material simulation methods (quantum chemistry methods, molecular dynamics, Monte Carlo, phase field, etc.), extensive adoption of computing technologies (high-throughput, artificial intelligence, machine learning,...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Dec 17, 2022
Large skin defects caused by accidents or disease can cause fluid loss, water and electrolyte disorders, hypoproteinemia and serious infection and remain a difficult problem in clinical practice. In situ bioprinting is a promising, recently developed...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Oct 13, 2022
Multifunctional nanocomposites which exhibit well-defined physical properties and encode spatiotemporally-controlled responses are emerging as components for advanced responsive systems. For biomedical applications magnetic nanocomposite materials ha...
Sensors (Basel, Switzerland)
Oct 10, 2022
Personalised healthcare has seen significant improvements due to the introduction of health monitoring technologies that allow wearable devices to unintrusively monitor physiological parameters such as heart health, blood pressure, sleep patterns, an...
Tissue engineering. Part A
Sep 26, 2022
Machine learning (ML) and artificial intelligence have accelerated scientific discovery, augmented clinical practice, and deepened fundamental understanding of many biological phenomena. ML technologies have now been applied to diverse areas of tissu...
Proceedings of the National Academy of Sciences of the United States of America
Sep 26, 2022
Collagen is the most abundant structural protein in humans, providing crucial mechanical properties, including high strength and toughness, in tissues. Collagen-based biomaterials are, therefore, used for tissue repair and regeneration. Utilizing col...
ACS biomaterials science & engineering
Sep 23, 2022
Collagen is one of the most important structural proteins in biology, and its structural hierarchy plays a crucial role in many mechanically important biomaterials. Here, we demonstrate how transformer models can be used to predict, directly from the...
Science (New York, N.Y.)
Sep 15, 2022
Deep learning generative approaches provide an opportunity to broadly explore protein structure space beyond the sequences and structures of natural proteins. Here, we use deep network hallucination to generate a wide range of symmetric protein homo-...