AIMC Topic: Biotechnology

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Precision Regulation Approach: A COVID-19 Triggered Regulatory Drive in South Korea.

Frontiers in public health
COVID-19 has triggered various changes in our everyday lives and how we conceptualize the functions of governments. Some areas require stricter forms of regulation while others call for deregulation. The challenge for the regulatory authorities is to...

Best practices for artificial intelligence in life sciences research.

Drug discovery today
We describe 11 best practices for the successful use of artificial intelligence and machine learning in pharmaceutical and biotechnology research at the data, technology and organizational management levels.

A machine learning toolkit for genetic engineering attribution to facilitate biosecurity.

Nature communications
The promise of biotechnology is tempered by its potential for accidental or deliberate misuse. Reliably identifying telltale signatures characteristic to different genetic designers, termed 'genetic engineering attribution', would deter misuse, yet i...

Sequence-to-function deep learning frameworks for engineered riboregulators.

Nature communications
While synthetic biology has revolutionized our approaches to medicine, agriculture, and energy, the design of completely novel biological circuit components beyond naturally-derived templates remains challenging due to poorly understood design rules....

Biosystems Design by Machine Learning.

ACS synthetic biology
Biosystems such as enzymes, pathways, and whole cells have been increasingly explored for biotechnological applications. However, the intricate connectivity and resulting complexity of biosystems poses a major hurdle in designing biosystems with desi...

Future development of artificial organs related with cutting edge emerging technology and their regulatory assessment: PMDA's perspective.

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs
Future development of innovative artificial organs is closely related with cutting edge emerging technology. These technologies include brain machine or computer interface, organs made by three dimensional bioprinting, organs designed from induced-pl...

High-Throughput Screening Technology in Industrial Biotechnology.

Trends in biotechnology
Based on the development of automatic devices and rapid assay methods, various high-throughput screening (HTS) strategies have been established for improving the performance of industrial microorganisms. We discuss the most significant factors that c...

The Times they Are a-Changin' - Healthcare 4.0 Is Coming!

Journal of medical systems
The Industrial Revolution brought new economics and new epidemic patterns to the people, which formed the healthcare 1.0 that focused on public health solutions. The emergence of large production concept and technology brought healthcare to 2.0. Bigg...

Integrated Robotic Mini Bioreactor Platform for Automated, Parallel Microbial Cultivation With Online Data Handling and Process Control.

SLAS technology
During process development, the experimental search space is defined by the number of experiments that can be performed in specific time frames but also by its sophistication (e.g., inputs, sensors, sampling frequency, analytics). High-throughput liq...

Metabolic cost adaptations during training with a soft exosuit assisting the hip joint.

Scientific reports
Different adaptation rates have been reported in studies involving ankle exoskeletons designed to reduce the metabolic cost of their wearers. This work aimed to investigate energetic adaptations occurring over multiple training sessions, while walkin...