Although contemporary practice in in vitro fertilization (IVF) favors embryo transfer at blastocyst stage, several centres worldwide employ cleavage-stage Day-3 embryo transfers. The advantage of cultures extended to Day-5 and beyond, is to ensure th...
The implantation potential of an embryo is intricately linked to the quality of its blastocyst. Consequently, achieving an objective and precise identification of blastocyst morphology is imperative. The purpose of this study is to focus on the struc...
BACKGROUND: In assisted reproductive technology, evaluating the quality of the embryo is crucial when selecting the most viable embryo for transferring to a woman. Assessment also plays an important role in determining the optimal transfer time, eith...
Systems biology in reproductive medicine
Aug 26, 2025
Early embryo development and competence mechanisms are paramount to ART's success but are still underexplored in human-relevant animal models. Clinical embryo evaluation remains largely based on subjectively evaluated morphological characteristics. I...
Predicting blastocyst formation poses significant challenges in reproductive medicine and critically influences clinical decision-making regarding extended embryo culture. While previous research has primarily focused on determining whether an IVF cy...
Evaluating cumulus-oocyte complex (COC) morphology is commonly used to assess oocyte quality. However, clear guidelines on interpreting COC morphology data are lacking as this evaluation method is subjective. In the present study, individual in vitro...
Accurate embryo assessment on embryonic day 3 of assisted reproductive technology (ART) is crucial for deciding whether to continue the culture until day 5 (blastocyst stage) or opt for earlier transfer or cryopreservation. Prolonged culture often im...
Reproductive biology and endocrinology : RB&E
Jan 31, 2025
BACKGROUND: Artificial intelligence (AI) models analyzing embryo time-lapse images have been developed to predict the likelihood of pregnancy following in vitro fertilization (IVF). However, limited research exists on methods ensuring AI consistency ...
Current opinion in nephrology and hypertension
Jan 20, 2025
PURPOSE OF REVIEW: This review explores the variability in preimplantation kidney biopsy processing methods, emphasizing their impact on histological interpretation and allocation decisions driven by biopsy findings. With the increasing use of artifi...
The use of time lapse systems (TLS) in In Vitro Fertilization (IVF) labs to record developing embryos has paved the way for deep-learning based computer vision algorithms to assist embryologists in their morphokinetic evaluation. Today, most of the l...
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