AIMC Topic: Brachytherapy

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Machine Segmentation of Pelvic Anatomy in MRI-Assisted Radiosurgery (MARS) for Prostate Cancer Brachytherapy.

International journal of radiation oncology, biology, physics
PURPOSE: To investigate machine segmentation of pelvic anatomy in magnetic resonance imaging (MRI)-assisted radiosurgery (MARS) for prostate cancer using prostate brachytherapy MRIs acquired with different pulse sequences and image contrasts.

Label-driven magnetic resonance imaging (MRI)-transrectal ultrasound (TRUS) registration using weakly supervised learning for MRI-guided prostate radiotherapy.

Physics in medicine and biology
Registration and fusion of magnetic resonance imaging (MRI) and transrectal ultrasound (TRUS) of the prostate can provide guidance for prostate brachytherapy. However, accurate registration remains a challenging task due to the lack of ground truth r...

RapidBrachyDL: Rapid Radiation Dose Calculations in Brachytherapy Via Deep Learning.

International journal of radiation oncology, biology, physics
PURPOSE: Detailed and accurate absorbed dose calculations from radiation interactions with the human body can be obtained with the Monte Carlo (MC) method. However, the MC method can be slow for use in the time-sensitive clinical workflow. The aim of...

Conventional vs machine learning-based treatment planning in prostate brachytherapy: Results of a Phase I randomized controlled trial.

Brachytherapy
PURPOSE: The purpose of this study was to evaluate the noninferiority of Day 30 dosimetry between a machine learning-based treatment planning system for prostate low-dose-rate (LDR) brachytherapy and the conventional, manual planning technique. As a ...

Automatic prostate segmentation using deep learning on clinically diverse 3D transrectal ultrasound images.

Medical physics
PURPOSE: Needle-based procedures for diagnosing and treating prostate cancer, such as biopsy and brachytherapy, have incorporated three-dimensional (3D) transrectal ultrasound (TRUS) imaging to improve needle guidance. Using these images effectively ...

Automatic detection of brachytherapy seeds in 3D ultrasound images using a convolutional neural network.

Physics in medicine and biology
A novel approach for automatic localization of brachytherapy seeds in 3D transrectal ultrasound (TRUS) images, using machine learning based algorithm, is presented. 3D radiofrequency ultrasound signals were collected from 13 patients using the linear...

Deep-learning assisted automatic digitization of interstitial needles in 3D CT image based high dose-rate brachytherapy of gynecological cancer.

Physics in medicine and biology
Digitization of interstitial needles is a complicated and tedious process for the treatment planning of 3D CT image based interstitial high dose-rate brachytherapy (HDRBT) of gynecological cancer. We developed a deep-learning assisted auto-digitizati...

Generative adversarial networks (GAN) for compact beam source modelling in Monte Carlo simulations.

Physics in medicine and biology
A method is proposed and evaluated to model large and inconvenient phase space files used in Monte Carlo simulations by a compact generative adversarial network (GAN). The GAN is trained based on a phase space dataset to create a neural network, call...

Fully automatic catheter segmentation in MRI with 3D convolutional neural networks: application to MRI-guided gynecologic brachytherapy.

Physics in medicine and biology
External-beam radiotherapy followed by high dose rate (HDR) brachytherapy is the standard-of-care for treating gynecologic cancers. The enhanced soft-tissue contrast provided by magnetic resonance imaging (MRI) makes it a valuable imaging modality fo...

Deep-learning-assisted automatic digitization of applicators in 3D CT image-based high-dose-rate brachytherapy of gynecological cancer.

Brachytherapy
PURPOSE: Applicator digitization is one of the most critical steps in 3D high-dose-rate brachytherapy (HDRBT) treatment planning. Motivated by recent advances in deep-learning, we propose a deep-learning-assisted applicator digitization method for 3D...