Studies in health technology and informatics
Jun 6, 2022
Gliomas are the most common neuroepithelial brain tumors, different by various biological tissue types and prognosis. They could be graded with four levels according to the 2007 WHO classification. The emergence of non-invasive histological and molec...
BACKGROUND: Diagnostic classification of diffuse gliomas now requires an assessment of molecular features, often including IDH-mutation and 1p19q-codeletion status. Because genetic testing requires an invasive process, an alternative noninvasive appr...
Frontiers in bioscience (Landmark edition)
Mar 16, 2022
BACKGROUND: Dynamic contrast-enhanced (DCE) MRI is widely used to assess vascular perfusion and permeability in cancer. In small animal applications, conventional modeling of pharmacokinetic (PK) parameters from DCE MRI images is complex and time con...
MATERIALS AND METHODS: This monocentric retrospective study leveraged 200 multiparametric brain MRIs acquired between November 2019 and February 2020 at Gustave Roussy Cancer Campus (Villejuif, France). A total of 145 patients were included: 107 form...
The heterogeneity of brain tumours at the molecular, metabolic and structural levels poses significant challenge for accurate tissue characterisation. Artificial intelligence and radiomics have emerged as valuable tools to analyse quantitative featur...
In the last decades, modern medicine has evolved into a data-centered discipline, generating massive amounts of granular high-dimensional data exceeding human comprehension. With improved computational methods, machine learning and artificial intelli...
According to the International Agency for Research on Cancer (IARC), the mortality rate due to brain tumors is 76%. It is required to detect the brain tumors as early as possible and to provide the patient with the required treatment to avoid any fat...
Although the prognosis of lower-grade glioma (LGG) patients is better than others, outcomes are highly heterogeneous. Isocitrate dehydrogenase (IDH) mutation and 1p/19q codeletion status can identify patient subsets with different prognosis. However,...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Nov 1, 2021
Magnetic Resonance Imaging (MRI) technology has been widely applied to generate high-resolution images for brain tumor diagnosis. However, manual image reading is very time and labor consuming. Instead, automatic tumor detection based on deep learnin...