BACKGROUND: Peritoneal metastasis (PM) after the rupture of hepatocellular carcinoma (HCC) is a critical issue that negatively affects patient prognosis. Machine learning models have shown great potential in predicting clinical outcomes; however, the...
Combinatorial chemistry & high throughput screening
Jan 1, 2025
BACKGROUND: Necroptosis, a recently identified mechanism of programmed cell death, exerts significant influence on various aspects of cancer biology, including tumor cell proliferation, stemness, metastasis, and immunosuppression. However, the role o...
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
Dec 30, 2024
Hepatocellular carcinoma (HCC) is a prevalent cancer that significantly contributes to mortality globally, primarily due to its late diagnosis. Early detection is crucial yet challenging. This study leverages the potential of deep learning (DL) techn...
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
Dec 16, 2024
Since its advent, artificial intelligence (AI) has been continuously researched, and substantial progress has been made in many fields, such as the diagnosis and therapies for cancer. Due to the advantages of high efficiency, rapidity, and precision,...
Recent studies suggest cGAS-STING pathway may play a crucial role in the genesis and development of hepatocellular carcinoma (HCC), closely associated with classical pathways and tumor immunity. We aimed to develop models predicting survival and anti...
Clinical cancer research : an official journal of the American Association for Cancer Research
Nov 15, 2024
PURPOSE: The spatial variability and clinical relevance of the tumor immune microenvironment (TIME) are still poorly understood for hepatocellular carcinoma (HCC). In this study, we aim to develop a deep learning (DL)-based image analysis model for t...
This letter comments on the article that developed and tested a machine learning model that predicts lymphovascular invasion/perineural invasion status by combining clinical indications and spectral computed tomography characteristics accurately. We ...
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
Oct 7, 2024
BACKGROUND/AIMS: Hepatocellular carcinoma (HCC) represents a primary liver malignancy with a multifaceted molecular landscape. The interplay between liquid-liquid phase separation (LLPS) and ferroptosis-a regulated form of cell death-has garnered int...
Nan fang yi ke da xue xue bao = Journal of Southern Medical University
Sep 20, 2024
OBJECTIVE: To establish a deep learning model for testing the feasibility of combining magnetic resonance imaging (MRI) deep learning features with clinical features for preoperative prediction of cytokeratin 19 (CK19) status of hepatocellular carcin...