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Cell Transplantation

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Robotic adherent cell injection for characterizing cell-cell communication.

IEEE transactions on bio-medical engineering
Compared to robotic injection of suspended cells (e.g., embryos and oocytes), fewer attempts were made to automate the injection of adherent cells (e.g., cancer cells and cardiomyocytes) due to their smaller size, highly irregular morphology, small t...

Development of a Microforce Sensor and Its Array Platform for Robotic Cell Microinjection Force Measurement.

Sensors (Basel, Switzerland)
Robot-assisted cell microinjection, which is precise and can enable a high throughput, is attracting interest from researchers. Conventional probe-type cell microforce sensors have some real-time injection force measurement limitations, which prevent...

Biodegradable microrobots for targeting cell delivery.

Medical hypotheses
These days, cell delivery is considered a potential method for treatment of many genetic diseases or tissue regeneration applications. In conventional cell delivery methods, cells are encapsulated in or cultured on biocompatible polymers. However, th...

A Capsule-Type Microrobot with Pick-and-Drop Motion for Targeted Drug and Cell Delivery.

Advanced healthcare materials
A capsule-type microrobot exhibits "pick-and-drop" (P&D) motion to hold a particle within a confined volume and transports it via a corkscrewing motion. The P&D motion is possible because the capsule-type microrobot has two parts: a plunger and a cap...

Robot-Assisted Stereotactic Microinjection Method for Precision Cell Transplantation in Rat and Canine Models.

Cell transplantation
Cell transplantation is a promising approach for addressing neurodegenerative conditions. In this study, we developed a robot-assisted stereotactic microinjection system for transplanting cells. We evaluated the factors that affect cellular graft via...