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Cholesterol, LDL

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Machine learning-based prediction of LDL cholesterol: performance evaluation and validation.

PeerJ
OBJECTIVE: This study aimed to validate and optimize a machine learning algorithm for accurately predicting low-density lipoprotein cholesterol (LDL-C) levels, addressing limitations of traditional formulas, particularly in hypertriglyceridemia.

Deep learning-based LDL-C level prediction and explainable AI interpretation.

Computers in biology and medicine
This study investigates the use of deep learning (DL) models to predict low-density lipoprotein cholesterol (LDL-C) levels. The dataset obtained from New York-Presbyterian Hospital/Weill Cornell Medical Center includes triglycerides (TG), total chole...

Predicting low density lipoprotein cholesterol target attainment using machine learning in patients with coronary artery disease receiving moderate-dose statin therapy.

Scientific reports
Low-density lipoprotein cholesterol (LDL-C) is an important factor in the development of cardiovascular disease, making its management a key aspect of cardiovascular health. While high-dose statin therapy is often recommended for LDL-C reduction, car...

Comparison between statistical and machine learning methods to detect the hematological indices with the greatest influence on elevated serum levels of low-density lipoprotein cholesterol.

Chemistry and physics of lipids
INTRODUCTION: Elevated levels of low-density lipoprotein-cholesterol (LDL-C) is a significant risk factor for the development of cardiovascular diseases (CVD)s. Furthermore, studies have revealed an association between indices of the complete blood c...

Explainable artificial intelligence for LDL cholesterol prediction and classification.

Clinical biochemistry
INTRODUCTION: Monitoring LDL-C levels is essential in clinical practice because there is a direct relation between low-density lipoprotein cholesterol (LDL-C) levels and atherosclerotic heart disease risk. Therefore, measurement or estimate of LDL-C ...

A comparative evaluation of low-density lipoprotein cholesterol estimation: Machine learning algorithms versus various equations.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND: Given the critical importance of Low-density lipoprotein cholesterol (LDL-C) levels in determining cardiovascular risk, it is essential to measure LDL-C accurately. Since the Friedewald formula generates incorrect predictions in many circ...

TRENDS IN CHOLESTEROL AND LIPOPROTEINS ARE ASSOCIATED WITH ACUTE RESPIRATORY DISTRESS SYNDROME INCIDENCE AND DEATH AMONG SEPSIS PATIENTS.

Shock (Augusta, Ga.)
Objective: Compare changes in cholesterol and lipoprotein levels occurring in septic patients with and without acute respiratory distress syndrome (ARDS) and by survivorship. Methods: We reanalyzed data from prospective sepsis studies. Cholesterol an...

Cholesterol Levels, Hormone Replacement Therapy, and Incident Dementia among Older Adult Women.

Nutrients
Previous studies revealed that hormone replacement therapy (HRT) probably has a protective effect for preventing dementia in post-menopausal women. However, the results were still controversial. The association between cholesterol levels and incident...

Dataset dependency of low-density lipoprotein-cholesterol estimation by machine learning.

Annals of clinical biochemistry
OBJECTIVES: We evaluated the applicability of a machine learning-based low-density lipoprotein-cholesterol (LDL-C) estimation method and the influence of the characteristics of the training datasets.