AIMC Topic: Chromosome Mapping

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Statistical and Machine Learning Methods for eQTL Analysis.

Methods in molecular biology (Clifton, N.J.)
An immense amount of observable diversity exists for all traits and across global populations. In the post-genomic era, equipped with efficient sequencing capabilities and better genotyping methods, we are now able to more fully appreciate how regula...

Design of Knowledge Bases for Plant Gene Regulatory Networks.

Methods in molecular biology (Clifton, N.J.)
Developing a knowledge base that contains all the information necessary for the researcher studying gene regulation in a particular organism can be accomplished in four stages. This begins with defining the data scope. We describe here the necessary ...

Genome-wide discovery of miRNAs using ensembles of machine learning algorithms and logistic regression.

International journal of data mining and bioinformatics
In silico prediction of novel miRNAs from genomic sequences remains a challenging problem. This study presents a genome-wide miRNA discovery software package called GenoScan and evaluates two hairpin classification methods. These methods, one ensembl...