AIMC Topic: Circulating Tumor DNA

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Role of Machine Learning in Liquid Biopsy of Brain Tumours.

JPMA. The Journal of the Pakistan Medical Association
Liquid biopsy has multiple benefits and is used extensively in other fields of oncology, but its role in neuro-oncology has been limited so far. Multiple tumour-derived materials like circulating tumour cells (CTCs), tumour-educated platelets (TEPs),...

Unlocking Early Cancer Detection: Leveraging Machine Learning in Cell-Free DNA Analysis for Precision Oncology.

AMIA ... Annual Symposium proceedings. AMIA Symposium
This study introduces a groundbreaking approach to early cancer detection through the analysis of cell-free DNA (cfDNA), utilizing machine learning algorithms to navigate the complexities of low circulating tumor DNA (ctDNA) fractions and genetic het...

MSIsensor-ct: microsatellite instability detection using cfDNA sequencing data.

Briefings in bioinformatics
MOTIVATION: Microsatellite instability (MSI) is a promising biomarker for cancer prognosis and chemosensitivity. Techniques are rapidly evolving for the detection of MSI from tumor-normal paired or tumor-only sequencing data. However, tumor tissues a...