AIMC Topic: Clinical Trials, Phase II as Topic

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Utility of AI digital pathology as an aid for pathologists scoring fibrosis in MASH.

Journal of hepatology
BACKGROUND & AIMS: Intra and inter-pathologist variability poses a significant challenge in metabolic dysfunction-associated steatohepatitis (MASH) biopsy evaluation, leading to suboptimal selection of patients and confounded assessment of histologic...

Explainable machine learning prediction of edema adverse events in patients treated with tepotinib.

Clinical and translational science
Tepotinib is approved for the treatment of patients with non-small-cell lung cancer harboring MET exon 14 skipping alterations. While edema is the most prevalent adverse event (AE) and a known class effect of MET inhibitors including tepotinib, there...