Studies in health technology and informatics
May 15, 2025
Multimorbidity is increasingly prevalent as the population ages and individuals with multiple long-term conditions (MLTCs) live longer. Often each condition is treated by a separate clinician, which can lead to harmful drug-drug and drug-disease inte...
BACKGROUND: Classification is one of the most common tasks in artificial intelligence (AI) driven fields in dentistry and orthodontics. The AI abilities can significantly improve the orthodontist's critical mission to diagnose and treat patients prec...
MOTIVATION: Single-cell RNA sequencing (scRNA-seq) analysis relies heavily on effective clustering to facilitate numerous downstream applications. Although several machine learning methods have been developed to enhance single-cell clustering, most a...
Clustering is pivotal in deciphering cellular heterogeneity in single-cell RNA sequencing (scRNA-seq) data. However, it suffers from several challenges in handling the high dimensionality and complexity of scRNA-seq data. Especially when employing gr...
PURPOSE: Malnutrition remains a critical public health issue in low-income countries, significantly hindering economic development and contributing to over 50% of infant deaths. Under nutrition weakens immune systems, increasing susceptibility to com...
Machine learning (ML) is rapidly gaining traction in many areas of experimental molecular science for elucidating relationships and patterns in large or complex data sets. Historically, ML was largely the preserve of those with specialized training i...
In post-translational modification, covalent bonds on lysine and attached chemical groups significantly change proteins' physical and chemical properties. They shape protein structures, enhance function and stability, and are vital for physiological ...
Journal of the American Medical Informatics Association : JAMIA
Mar 1, 2025
OBJECTIVES: Clinical trials (CTs) are essential for improving patient care by evaluating new treatments' safety and efficacy. A key component in CT protocols is the study population defined by the eligibility criteria. This study aims to evaluate the...
Alzheimer's & dementia : the journal of the Alzheimer's Association
Feb 1, 2025
INTRODUCTION: Cognitive decline has become a growing public concern, yet large-scale exposure data identifying the contributing factors remain limited.
OBJECTIVE: Early detection of knee osteoarthritis is crucial for improving patient outcomes. While conventional imaging methods often fail to detect early changes and require specialized expertise for interpretation, this study aimed to investigate t...
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