AIMC Topic: Colitis, Ulcerative
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Anti-infliximab antibodies and low infliximab levels correlate with drug discontinuation in pediatric inflammatory bowel disease.
Journal of pediatric gastroenterology and nutrition
Dec 27, 2023
BACKGROUND: Infliximab (IFX) use is limited by loss of response often due to the development of anti-IFX antibodies and low drug levels.
Identifying risk factors of anti-TNF induced skin lesions and other adverse events in paediatric patients with inflammatory bowel disease.
Journal of pediatric gastroenterology and nutrition
Dec 10, 2023
OBJECTIVES: While higher infliximab (IFX) trough concentrations (TCs) are associated with better outcomes in patients with inflammatory bowel disease (IBD), they could pose a risk for adverse events (AEs), including IFX-induced skin lesions. Therefor...
A machine learning approach toward automating spatial identification of LAG3+/CD3+ cells in ulcerative colitis.
Scientific reports
Dec 8, 2023
Over the past decade, automation of digital image analysis has become commonplace in both research and clinical settings. Spurred by recent advances in artificial intelligence and machine learning (AI/ML), tissue sub-compartments and cellular phenoty...
Can artificial intelligence replace endoscopists when assessing mucosal healing in ulcerative colitis? A systematic review and diagnostic test accuracy meta-analysis.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Dec 5, 2023
BACKGROUNDS AND AIMS: Mucosal healing (MH) in inflammatory bowel diseases (IBD) is an important landmark for clinical decision making. Artificial intelligence systems (AI) that automatically deliver the grade of endoscopic inflammation may solve mode...
The Histological Detection of Ulcerative Colitis Using a No-Code Artificial Intelligence Model.
International journal of surgical pathology
Oct 25, 2023
Ulcerative colitis (UC) is an intractable disease that affects young adults. Histological findings are essential for its diagnosis; however, the number of diagnostic pathologists is limited. Herein, we used a no-code artificial intelligence (AI) plat...
Identifying Macrophage-Related Genes in Ulcerative Colitis Using Weighted Coexpression Network Analysis and Machine Learning.
Mediators of inflammation
Oct 25, 2023
Ulcerative colitis (UC) is an inflammatory bowel disease of unknown cause that typically affects the colon and rectum. Innate intestinal immunity, including macrophages, plays a significant role in the pathological development of UC. Using the CIBERS...
Artificial intelligence quantifying endoscopic severity of ulcerative colitis in gradation scale.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
Oct 11, 2023
OBJECTIVES: Existing endoscopic scores for ulcerative colitis (UC) objectively categorize disease severity based on the presence or absence of endoscopic findings; therefore, it may not reflect the range of clinical severity within each category. How...
Screening of the shared pathogenic genes of ulcerative colitis and colorectal cancer by integrated bioinformatics analysis.
Journal of cellular and molecular medicine
Jul 26, 2023
Ulcerative colitis (UC) is one of the high-risk pathogenic factors for colorectal cancer (CRC). However, the shared gene and signalling mechanisms between UC and CRC remain unclear. The goal of this study was to delve more into the probable causal re...
Deep learning model for distinguishing Mayo endoscopic subscore 0 and 1 in patients with ulcerative colitis.
Scientific reports
Jul 13, 2023
The aim of this study was to address the issue of differentiating between Mayo endoscopic subscore (MES) 0 and MES 1 using a deep learning model. A dataset of 492 ulcerative colitis (UC) patients who demonstrated MES improvement between January 2018 ...
Deep learning-based prediction model for diagnosing gastrointestinal diseases using endoscopy images.
International journal of medical informatics
Jul 5, 2023
BACKGROUND: Gastrointestinal (GI) infections are quite common today around the world. Colonoscopy or wireless capsule endoscopy (WCE) are noninvasive methods for examining the whole GI tract for abnormalities. Nevertheless, it requires a great deal o...
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