AIMC Topic: Colorectal Neoplasms

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Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers.

Annals of clinical and translational neurology
OBJECTIVE: Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk-prediction model incorpor...

A machine learning tool for identifying metastatic colorectal cancer in primary care.

Scandinavian journal of primary health care
BACKGROUND: Detection of colorectal cancer (CRC) is mainly achieved by clinical assessment. As new treatments become available for metastatic CRC (MCRC), it is important to accurately identify these patients.

A deep-learning model to predict the completeness of cytoreductive surgery in colorectal cancer with peritoneal metastasis☆.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
BACKGROUND: Colorectal cancer (CRC) with peritoneal metastasis (PM) is associated with poor prognosis. The Peritoneal Cancer Index (PCI) is used to evaluate the extent of PM and to select Cytoreductive Surgery (CRS). However, PCI score is not accurat...

Automated deep learning-based assessment of tumour-infiltrating lymphocyte density determines prognosis in colorectal cancer.

Journal of translational medicine
BACKGROUND: The presence of tumour-infiltrating lymphocytes (TILs) is a well-established prognostic biomarker across multiple cancer types, with higher TIL counts being associated with lower recurrence rates and improved patient survival. We aimed to...

Artificial intelligence and whole slide imaging, a new tool for the microsatellite instability prediction in colorectal cancer: Friend or foe?

Critical reviews in oncology/hematology
Colorectal cancer (CRC) is the third most common and second most deadly cancer worldwide. Despite advances in screening and treatment, CRC is heterogeneous and the response to therapy varies significantly, limiting personalized treatment options. Cer...

Development and validation of computer-aided detection for colorectal neoplasms using deep learning incorporated with computed tomography colonography.

BMC gastroenterology
OBJECTIVES: Computed tomography (CT) colonography is increasingly recognized as a valuable modality for diagnosing colorectal lesions, however, the interpretation workload remains challenging for physicians. Deep learning-based artificial intelligenc...

A deep-learning model for quantifying circulating tumour DNA from the density distribution of DNA-fragment lengths.

Nature biomedical engineering
The quantification of circulating tumour DNA (ctDNA) in blood enables non-invasive surveillance of cancer progression. Here we show that a deep-learning model can accurately quantify ctDNA from the density distribution of cell-free DNA-fragment lengt...

Machine Learning-Aided Identification of Fecal Extracellular Vesicle microRNA Signatures for Noninvasive Detection of Colorectal Cancer.

ACS nano
Colorectal cancer (CRC) remains a formidable threat to human health, with considerable challenges persisting in its diagnosis, particularly during the early stages of the malignancy. In this study, we elucidated that fecal extracellular vesicle micro...

Artificial intelligence assessment of tissue-dissection efficiency in laparoscopic colorectal surgery.

Langenbeck's archives of surgery
PURPOSE: Several surgical-skill assessment tools emphasize the importance of efficient tissue-dissection, whose assessment relies on human judgment and is thus subject to bias. Automated assessment may help solve this problem. This study aimed to ver...

Raman spectroscopy for colorectal tumor margin assessment: A promising tool for real-time surgical delimitation.

Talanta
Raman spectroscopy is a promising non-invasive technique not only for the rapid and accurate detection of colorectal cancer (CRC) but also for the identification of positive surgical margins. In this study, micro-Raman spectroscopy was used to explor...