BACKGROUND: CST4 is associated with various cancers but its diagnostic value in colorectal cancer (CRC) has not been clearly established. This study aims to further validate the diagnostic value of CST4 in colorectal cancer using random forest models...
UNLABELLED: Carcinoembryonic antigen (CEA) is a critical colorectal cancer (CRC) biomarker, but its mechanistic link to gut microbiota remains unclear. This study characterized gut microbiota differences between high-CEA (H-CEA) and low-CEA (L-CEA) C...
BACKGROUND: Static carcinoembryonic antigen (CEA) levels are well‑established prognostic markers in patients with gastric cancer, but the significance of their dynamic trajectories over time has rarely been reported.
Pancreatic cancer remains one of the deadliest malignancies due to its silent progression and lack of early diagnostic tools. Here, we report a light-addressable photoelectrochemical (LAMT-PEC) biosensing system featuring single-atom Au-TiO photoelec...
Lung cancer remains the leading cause of cancer-related mortality worldwide, largely due to late-stage diagnosis. Early detection is critical for improving patient outcomes, yet current screening methods, such as low-dose computed tomography (CT), of...
Cancer control : journal of the Moffitt Cancer Center
May 7, 2025
IntroductionEarly diagnosis of colorectal cancer (CRC) poses a significant clinical challenge. This study aims to develop machine learning (ML) models for CRC risk prediction using clinical laboratory data.MethodsThis retrospective, single-center stu...
The detection of early-stage diseases is often impeded by the low concentrations of protein biomarkers, necessitating sophisticated and costly technologies. In response, we have developed an advanced cyber-physical system that integrates blood plasma...
Early diagnosis and screening of tumor markers are essential for effective cancer treatment and improve the treatment efficiency and prognosis of tumor recurrence and metastasis. In this study, a split-ring resonator (SRR) circuit based on an interdi...
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Jun 20, 2024
BACKGROUND: Colorectal cancer has a high incidence and mortality rate due to a low rate of early diagnosis. Therefore, efficient diagnostic methods are urgently needed.
Clinical chemistry and laboratory medicine
Dec 14, 2023
OBJECTIVES: Misidentification errors in tumor marker tests can lead to serious diagnostic and treatment errors. This study aims to develop a method for detecting these errors using a machine learning (ML)-based delta check approach, overcoming limita...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.