AIMC Topic: Cross-Over Studies

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Evaluation of the pharmacokinetic drug-drug interaction between the antiretroviral agents fostemsavir and maraviroc: a single-sequence crossover study in healthy participants.

HIV research & clinical practice Mar 14, 2022
BACKGROUND: Fostemsavir is an oral prodrug of temsavir, a first-in-class attachment inhibitor that binds HIV-1 gp120, preventing initial HIV attachment and entry into host immune cells.
Cross-Over Studies Healthy Volunteers Humans Maraviroc Adult Drug Interactions Anti-HIV Agents Anti-Retroviral Agents Piperazines Organophosphates
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Comparative effects of EMG-driven robot-assisted therapy versus task-oriented training on motor and daily function in patients with stroke: a randomized cross-over trial.

Journal of neuroengineering and rehabilitation Jan 16, 2022
BACKGROUND: Robot-assisted hand training has shown positive effects on promoting neuromuscular control. Since both robot-assisted therapy and task-oriented training are often used in post-stroke rehabilitation, we raised the question of whether two i...
Humans Treatment Outcome Cross-Over Studies Upper Extremity Stroke Rehabilitation Recovery of Function Robotics Stroke
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Automatic Pancreatic Cyst Lesion Segmentation on EUS Images Using a Deep-Learning Approach.

Sensors (Basel, Switzerland) Dec 30, 2021
The automatic segmentation of the pancreatic cyst lesion (PCL) is essential for the automated diagnosis of pancreatic cyst lesions on endoscopic ultrasonography (EUS) images. In this study, we proposed a deep-learning approach for PCL segmentation on...
Humans Deep Learning Image Processing, Computer-Assisted Cross-Over Studies Pancreatic Cyst Endosonography
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Neuroenhancement of surgeons during robotic suturing.

Surgical endoscopy Nov 1, 2021
BACKGROUND: The initial phases of robotic surgical skills acquisition are associated with poor technical performance, such as low knot-tensile strength (KTS). Transcranial direct-current stimulation (tDCS) can improve force and accuracy in motor task...
Robotic Surgical Procedures Surgeons Humans Cross-Over Studies Male Robotics Transcranial Direct Current Stimulation Double-Blind Method
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A Combined Hot and Hypoxic Environment during Maximal Cycling Sprints Reduced Muscle Oxygen Saturation: A Pilot Study.

Journal of sports science & medicine Oct 1, 2021
The present study investigated the effects of a combined hot and hypoxic environment on muscle oxygenation during repeated 15-s maximal cycling sprints. In a single-blind, cross-over study, nine trained sprinters performed three 15-s maximal cycling ...
Hypoxia Quadriceps Muscle Oxygen Saturation Humans Single-Blind Method Pilot Projects Cross-Over Studies
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Robot-Assisted Gait Training in Patients with Multiple Sclerosis: A Randomized Controlled Crossover Trial.

Medicina (Kaunas, Lithuania) Jul 14, 2021
Gait disorders represent one of the most disabling aspects in multiple sclerosis (MS) that strongly influence patient quality of life. The improvement of walking ability is a primary goal for rehabilitation treatment. The aim of this study is to eva...
Humans Quality of Life Exercise Therapy Cross-Over Studies Multiple Sclerosis Robotics Walking Gait
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Added Value of Deep Learning-based Detection System for Multiple Major Findings on Chest Radiographs: A Randomized Crossover Study.

Radiology Mar 23, 2021
Background Previous studies assessing the effects of computer-aided detection on observer performance in the reading of chest radiographs used a sequential reading design that may have biased the results because of reading order or recall bias. Purpo...
Radiography, Thoracic Cross-Over Studies Observer Variation Female Sensitivity and Specificity Male Middle Aged Deep Learning Lung Diseases Humans Retrospective Studies Republic of Korea
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Prediction of cerebral perfusion pressure during CPR using electroencephalogram in a swine model of ventricular fibrillation.

The American journal of emergency medicine Feb 25, 2021
BACKGROUND: Measuring the quality of cardiopulmonary resuscitation (CPR) is important for improving outcomes in cardiac arrest. Cerebral perfusion pressure (CePP) could represent cerebral circulation during CPR, but it is difficult to measure non-inv...
Cardiopulmonary Resuscitation Ventricular Fibrillation Animals Swine Disease Models, Animal Electroencephalography Cross-Over Studies Machine Learning Cerebrovascular Circulation Female
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Effects of robot viscous forces on arm movements in chronic stroke survivors: a randomized crossover study.

Journal of neuroengineering and rehabilitation Nov 24, 2020
BACKGROUND: Our previous work showed that speed is linked to the ability to recover in chronic stroke survivors. Participants moving faster on the first day of a 3-week study had greater improvements on the Wolf Motor Function Test.
Middle Aged Robotics Stroke Cross-Over Studies Arm Viscosity Female Aged Male Humans Stroke Rehabilitation Movement Survivors
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Impact of haptic feedback on applied intracorporeal forces using a novel surgical robotic system-a randomized cross-over study with novices in an experimental setup.

Surgical endoscopy Jul 22, 2020
BACKGROUND: Most currently used surgical robots have no force feedback; the next generation displays forces visually. A novel single-port robotic surgical system called FLEXMIN has been developed. Through an outer diameter of 38 mm, two instruments a...
Cross-Over Studies Feedback Robotics Robotic Surgical Procedures Humans Learning
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