AIMC Topic: Data Interpretation, Statistical

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A novel missing data imputation approach based on clinical conditional Generative Adversarial Networks applied to EHR datasets.

Computers in biology and medicine
The missing data mechanism is a relevant problem in Machine Learning (ML) and biomedical informatics communities. Real-world Electronic Health Record (EHR) datasets comprise several missing values, thus revealing a high level of spatiotemporal sparsi...

Interpretable machine learning for psychological research: Opportunities and pitfalls.

Psychological methods
In recent years, machine learning methods have become increasingly popular prediction methods in psychology. At the same time, psychological researchers are typically not only interested in making predictions about the dependent variable, but also in...

An introduction to causal inference for pharmacometricians.

CPT: pharmacometrics & systems pharmacology
As formal causal inference begins to play a greater role in disciplines that intersect with pharmacometrics, such as biostatistics, epidemiology, and artificial intelligence/machine learning, pharmacometricians may increasingly benefit from a basic f...

Evaluation of machine learning methods for covariate data imputation in pharmacometrics.

CPT: pharmacometrics & systems pharmacology
Missing data create challenges in clinical research because they lead to loss of statistical power and potentially to biased results. Missing covariate data must be handled with suitable approaches to prepare datasets for pharmacometric analyses, suc...

Mediation analysis using Bayesian tree ensembles.

Psychological methods
We present a general framework for causal mediation analysis using nonparametric Bayesian methods in the potential outcomes framework. Our model, which we refer to as the Bayesian causal mediation forests model, combines recent advances in Bayesian m...

A Novel Reformed Reduced Kernel Extreme Learning Machine with RELIEF-F for Classification.

Computational intelligence and neuroscience
With the exponential growth of the Internet population, scientists and researchers face the large-scale data for processing. However, the traditional algorithms, due to their complex computation, are not suitable for the large-scale data, although th...

Missing data imputation in clinical trials using recurrent neural network facilitated by clustering and oversampling.

Biometrical journal. Biometrische Zeitschrift
In clinical practice, the composition of missing data may be complex, for example, a mixture of missing at random (MAR) and missing not at random (MNAR) assumptions. Many methods under the assumption of MAR are available. Under the assumption of MNAR...

A machine learning pipeline for classification of cetacean echolocation clicks in large underwater acoustic datasets.

PLoS computational biology
Machine learning algorithms, including recent advances in deep learning, are promising for tools for detection and classification of broadband high frequency signals in passive acoustic recordings. However, these methods are generally data-hungry and...

A Simulation Study to Compare the Predictive Performance of Survival Neural Networks with Cox Models for Clinical Trial Data.

Computational and mathematical methods in medicine
BACKGROUND: Studies focusing on prediction models are widespread in medicine. There is a trend in applying machine learning (ML) by medical researchers and clinicians. Over the years, multiple ML algorithms have been adapted to censored data. However...

A weighted patient network-based framework for predicting chronic diseases using graph neural networks.

Scientific reports
Chronic disease prediction is a critical task in healthcare. Existing studies fulfil this requirement by employing machine learning techniques based on patient features, but they suffer from high dimensional data problems and a high level of bias. We...