AIMC Topic: Deep Learning

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Deep learning driven de novo drug design based on gastric proton pump structures.

Communications biology
Existing drugs often suffer in their effectiveness due to detrimental side effects, low binding affinity or pharmacokinetic problems. This may be overcome by the development of distinct compounds. Here, we exploit the rich structural basis of drug-bo...

Automatic identification of posteroanterior cephalometric landmarks using a novel deep learning algorithm: a comparative study with human experts.

Scientific reports
This study aimed to propose a fully automatic posteroanterior (PA) cephalometric landmark identification model using deep learning algorithms and compare its accuracy and reliability with those of expert human examiners. In total, 1032 PA cephalometr...

Real-time and accurate estimation of surgical hemoglobin loss using deep learning-based medical sponges image analysis.

Scientific reports
Real-time and accurate estimation of surgical hemoglobin (Hb) loss is essential for fluid resuscitation management and evaluation of surgical techniques. In this study, we aimed to explore a novel surgical Hb loss estimation method using deep learnin...

Selecting cardiac magnetic resonance images suitable for annotation of pulmonary arteries using an active-learning based deep learning model.

Scientific reports
An increasing and aging patient population poses a growing burden on healthcare professionals. Automation of medical imaging diagnostics holds promise for enhancing patient care and reducing manpower required to accommodate an increasing patient-popu...

A state-of-the-art review on deep learning for estimating eloquent cortex from resting-state fMRI.

Neurosurgical review
Deep learning algorithms have greatly improved our ability to estimate eloquent cortex regions from resting-state brain scans for patients about to undergo neurosurgery. The use of deep learning has the potential to fully automate functional mapping ...

Deep Learning Neural Network-Guided Detection of Asbestos Bodies in Bronchoalveolar Lavage Samples.

Acta cytologica
INTRODUCTION: Asbestos is a global occupational health hazard, and exposure to it by inhalation predisposes to interstitial as well as malignant pulmonary morbidity. Over time, asbestos fibers embedded in lung tissue can become coated with iron-rich ...

Deep Learning-Based Model for Automatic Assessment of Anterior Angle Chamber in Ultrasound Biomicroscopy.

Ultrasound in medicine & biology
OBJECTIVE: The goal of the work described here was to develop and assess a deep learning-based model that could automatically segment anterior chamber angle (ACA) tissues; classify iris curvature (I-Curv), iris root insertion (IRI), and angle closure...

Three-dimensional CT imaging in extensor tendons using deep learning reconstruction: optimal reconstruction parameters and the influence of dose.

Physical and engineering sciences in medicine
The purpose of this study was to assess the optimal reconstruction parameters and the influence of tube current in extensor tendons three-dimensional computed tomography (3D CT) using deep learning reconstruction, using iterative reconstruction as a ...

A deep learning system to monitor and assess rehabilitation exercises in home-based remote and unsupervised conditions.

Computers in biology and medicine
In the domain of physical rehabilitation, the progress in machine learning and the availability of cost-effective motion capture technologies have paved the way for innovative systems capable of capturing human movements, automatically analyzing reco...

Exploring and validating the prognostic value of pathomics signatures and genomics in patients with cutaneous melanoma based on bioinformatics and deep learning.

Medical physics
BACKGROUND: Cutaneous melanoma (CM) is the most common malignant tumor of the skin. Our study aimed to investigate the prognostic value of pathomics signatures for CM by combining pathomics and genomics.