Artificial intelligence (AI) models based on deep learning now represent the state of the art for making functional predictions in genomics research. However, the underlying basis on which predictive models make such predictions is often unknown. For...
European journal of medicinal chemistry
Oct 3, 2022
SARS-CoV-2 3CL protease is one of the key targets for drug development against COVID-19. Most known SARS-CoV-2 3CL protease inhibitors act by covalently binding to the active site cysteine. Yet, computational screens against this enzyme were mainly f...
Handwriting recognition is regarded as a dynamic and inspiring topic in the exploration of pattern recognition and image processing. It has many applications including a blind reading aid, computerized reading, and processing for paper documents, mak...
Medical & biological engineering & computing
Oct 3, 2022
The precise segmentation of multimodal MRI images is the primary stage of tumor diagnosis and treatment. Current segmentation strategies often underutilize multiscale features, which can easily lead to loss of contextual information, reduction of low...
Medical & biological engineering & computing
Oct 3, 2022
This paper presents an automated method for detection of the diagnostically prominent frames containing optic nerve sheath (ONS) from ocular ultrasonography video using deep learning; such frames are referred to as "Good View" frames in this paper. V...
BACKGROUND: Mucin depletion is one of the histological indicators of clinical relapse among patients with ulcerative colitis (UC). Mucin depletion is evaluated semiquantitatively by pathologists using histological images. Therefore, the interobserver...
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Oct 3, 2022
Advances in electron microscopy (EM) such as electron tomography and focused ion-beam scanning electron microscopy provide unprecedented, three-dimensional views of cardiac ultrastructures within sample volumes ranging from hundreds of nanometres to ...
The recent investigation has started for evaluating the human respiratory sounds, like voice recorded, cough, and breathing from hospital confirmed Covid-19 tools, which differs from healthy person's sound. The cough-based detection of Covid-19 also ...
Chest X-ray (CXR) images are considered useful to monitor and investigate a variety of pulmonary disorders such as COVID-19, Pneumonia, and Tuberculosis (TB). With recent technological advancements, such diseases may now be recognized more precisely ...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Oct 3, 2022
BACKGROUND PURPOSE: This study focused on developing a fast Monte Carlo (MC) plan verification platform via a deep learning (DL)-based denoising approach. It can maintain the MC dose calculation accuracy while significantly reducing the computation t...
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