Journal of chemical information and modeling
Jan 25, 2021
In the world plagued by the emergence of new diseases, it is essential that we accelerate the drug design process to develop new therapeutics against them. In recent years, deep learning-based methods have shown some success in ligand-based drug desi...
Medical & biological engineering & computing
Jan 25, 2021
Deep learning (DL) has been successfully applied to the diagnosis of ophthalmic diseases. However, rare diseases are commonly neglected due to insufficient data. Here, we demonstrate that few-shot learning (FSL) using a generative adversarial network...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Jan 25, 2021
PURPOSE: A novel fast kilovoltage switching dual-energy CT with deep learning [Deep learning based-spectral CT (DL-Spectral CT)], which generates a complete sinogram for each kilovolt using deep learning views that complement the measured views at ea...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Jan 25, 2021
Drug combinations targeting multiple targets/pathways are believed to be able to reduce drug resistance. Computational models are essential for novel drug combination discovery. In this study, we proposed a new simplified deep learning model, for dr...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Jan 25, 2021
Recent research in predicting protein secondary structure populations (SSP) based on Nuclear Magnetic Resonance (NMR) chemical shifts has helped quantitatively characterise the structural conformational properties of intrinsically disordered proteins...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Jan 25, 2021
Chest radiographs are the most common diagnostic exam in emergency rooms and intensive care units today. Recently, a number of researchers have begun working on large chest X-ray datasets to develop deep learning models for recognition of a handful o...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Jan 25, 2021
We apply deep learning-based language models to the task of patient cohort retrieval (CR) with the aim to assess their efficacy. The task ofCR requires the extraction of relevant documents from the electronic health records (EHRs) on the basis of a g...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Jan 25, 2021
Wrist accelerometers for assessing hallmark measures of physical activity (PA) are rapidly growing with the advent of smartwatch technology. Given the growing popularity of wrist-worn accelerometers, there needs to be a rigorous evaluation for recogn...
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