Nucleic acids research
Feb 22, 2022
For many RNA molecules, the secondary structure is essential for the correct function of the RNA. Predicting RNA secondary structure from nucleotide sequences is a long-standing problem in genomics, but the prediction performance has reached a platea...
Microscopy (Oxford, England)
Feb 18, 2022
We review the growing use of machine learning in electron microscopy (EM) driven in part by the availability of fast detectors operating at kiloHertz frame rates leading to large data sets that cannot be processed using manually implemented algorithm...
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
Feb 18, 2022
OBJECTIVE: To establish a deep learning algorithm that can accurately determine three-dimensional facial anatomical landmarks, multi-view stacked hourglass convolutional neural networks (MSH-CNN) and to construct three-dimensional facial midsagittal ...
Optics express
Feb 14, 2022
An improved deep neural network incorporating attention mechanism and DSSIM loss function (AM_U_Net) is used to recover input images with speckles transmitted through a multimode fiber (MMF). The network is trained on a relatively small dataset and d...
Bioinformatics (Oxford, England)
Feb 7, 2022
MOTIVATION: Viruses, the most abundant biological entities on earth, are important components of microbial communities, and as major human pathogens, they are responsible for human mortality and morbidity. The identification of viral sequences from m...
Bioinformatics (Oxford, England)
Feb 7, 2022
MOTIVATION: With the development of single-cell RNA sequencing (scRNA-seq) techniques, increasingly more large-scale gene expression datasets become available. However, to analyze datasets produced by different experiments, batch effects among differ...
Bioinformatics (Oxford, England)
Feb 7, 2022
SUMMARY: DeepKG is an end-to-end deep learning-based workflow that helps researchers automatically mine valuable knowledge in biomedical literature. Users can utilize it to establish customized knowledge graphs in specified domains, thus facilitating...
Bioinformatics (Oxford, England)
Feb 7, 2022
MOTIVATION: DNA methylation plays a key role in a variety of biological processes. Recently, Nanopore long-read sequencing has enabled direct detection of these modifications. As a consequence, a range of computational methods have been developed to ...
Integrative and comparative biology
Feb 5, 2022
The goal of this vision paper is to investigate the possible role that advanced machine learning techniques, especially deep learning (DL), could play in the reintegration of various biological disciplines. To achieve this goal, a series of operation...
Translational vision science & technology
Feb 1, 2022
PURPOSE: To develop an automated diabetic retinopathy (DR) staging system using optical coherence tomography angiography (OCTA) images with a convolutional neural network (CNN) and to verify the feasibility of the system.