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Diabetic Foot

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SDC4 protein action and related key genes in nonhealing diabetic foot ulcers based on bioinformatics analysis and machine learning.

International journal of biological macromolecules
Diabetic foot ulcers (DFU) is a complication associated with diabetes characterised by high morbidity, disability, and mortality, involving chronic inflammation and infiltration of multiple immune cells. We aimed to identify the critical genes in non...

Advances in Machine Learning-Aided Thermal Imaging for Early Detection of Diabetic Foot Ulcers: A Review.

Biosensors
The prevention and early warning of foot ulcers are crucial in diabetic care; however, early microvascular lesions are difficult to detect and often diagnosed at later stages, posing serious health risks. Infrared thermal imaging, as a rapid and non-...

A few-shot diabetes foot ulcer image classification method based on deep ResNet and transfer learning.

Scientific reports
Diabetes foot ulcer (DFU) is one of the common complications of diabetes patients, which may lead to infection, necrosis and even amputation. Therefore, early diagnosis, classification of severity and related treatment are crucial for the patients. C...

Construction and validation of a deep learning-based diagnostic model for segmentation and classification of diabetic foot.

Frontiers in endocrinology
OBJECTIVE: This study aims to conduct an in-depth analysis of diabetic foot ulcer (DFU) images using deep learning models, achieving automated segmentation and classification of the wounds, with the goal of exploring the application of artificial int...

An interpreting machine learning models to predict amputation risk in patients with diabetic foot ulcers: a multi-center study.

Frontiers in endocrinology
BACKGROUND: Diabetic foot ulcers (DFUs) constitute a significant complication among individuals with diabetes and serve as a primary cause of nontraumatic lower-extremity amputation (LEA) within this population. We aimed to develop machine learning (...

Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers.

Frontiers in endocrinology
BACKGROUND: Diabetic foot ulcers (DFUs) are a serious complication of diabetes mellitus that manifests as chronic, non-healing wounds that have a significant impact on patients quality of life. Identifying key molecular targets associated with DFUs c...

A feature explainability-based deep learning technique for diabetic foot ulcer identification.

Scientific reports
Diabetic foot ulcers (DFUs) are a common and serious complication of diabetes, presenting as open sores or wounds on the sole. They result from impaired blood circulation and neuropathy associated with diabetes, increasing the risk of severe infectio...

An explainable deep learning model for diabetic foot ulcer classification using swin transformer and efficient multi-scale attention-driven network.

Scientific reports
Diabetic Foot Ulcer (DFU) is a severe complication of diabetes mellitus, resulting in significant health and socio-economic challenges for the diagnosed individual. Severe cases of DFU can lead to lower limb amputation in diabetic patients, making th...

A novel deep learning approach to classify 3D foot types of diabetic patients.

Scientific reports
Diabetes mellitus is a worldwide epidemic that leads to significant changes in foot shape, deformities, and ulcers. Precise classification of diabetic foot not only helps identify foot abnormalities but also facilitates personalized treatment and pre...

Establishing a clinical prediction model for diabetic foot ulcers in type 2 diabetic patients with lower extremity arteriosclerotic occlusion using machine learning.

Scientific reports
The burden of diabetic foot ulcers (DFU) is exacerbated in diabetic patients with concomitant arteriosclerotic occlusion disease (ASO) in the lower extremities, who experience more severe symptoms and poorer prognoses. The study aims to develop a pre...