AIMC Topic: Diabetic Foot

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Diabetic foot prevention, assessment, and management using innovative smart wearable technology: a systematic review.

Journal of neuroengineering and rehabilitation Jul 18, 2025
The diabetic foot (DF) is a chief culprit behind significant preventable morbidity and mortality in type-2-diabetes patients and the leading cause of non-traumatic lower-extremity amputations. Despite the clinically well-understood pathways to ulcera...
Humans Wearable Electronic Devices Diabetic Foot
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Unraveling the oxidative stress landscape in diabetic foot ulcers: insights from bulk RNA and single-cell RNA sequencing data.

Biology direct Jul 4, 2025
BACKGROUND: Oxidative stress plays a crucial role in the development of diabetic foot ulcers (DFU). However, its underlying mechanisms are not fully understood. The purpose of this study was to use bioinformatics and preliminary validation methods to...
Humans Oxidative Stress Single-Cell Analysis Sequence Analysis, RNA Diabetic Foot
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Social and Structural Determinants of Lower Extremity Amputations in Diabetes.

Current diabetes reports Jul 2, 2025
PURPOSE OF REVIEW: Lower extremity amputations (LEAs) are among the most severe complications of diabetes, with approximately 1.5 million procedures performed globally each year. This review explores the impact of social and structural determinants o...
Amputation, Surgical Diabetic Foot Social Determinants of Health Humans Socioeconomic Factors Health Services Accessibility Diabetes Mellitus Lower Extremity Healthcare Disparities
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Predicting diabetic peripheral neuropathy through advanced plantar pressure analysis: a machine learning approach.

Scientific reports Jul 1, 2025
Diabetic foot Ulceration (DFU) is a severe complication of diabetic foot syndrome, often leading to amputation. In patients with neuropathy, ulcer formation is facilitated by elevated plantar tissue stress under insensate feet. This study presents a ...
Female Aged Male Humans Machine Learning Algorithms Pressure Foot Diabetic Neuropathies Middle Aged Diabetic Foot
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Gaussian random fields as an abstract representation of patient metadata for multimodal medical image segmentation.

Scientific reports May 29, 2025
Growing rates of chronic wound occurrence, especially in patients with diabetes, has become a recent concerning trend. Chronic wounds are difficult and costly to treat, and have become a serious burden on health care systems worldwide. Innovative dee...
Diabetic Foot Metadata Normal Distribution Deep Learning Image Processing, Computer-Assisted Humans Algorithms
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A novel deep learning approach to classify 3D foot types of diabetic patients.

Scientific reports Apr 22, 2025
Diabetes mellitus is a worldwide epidemic that leads to significant changes in foot shape, deformities, and ulcers. Precise classification of diabetic foot not only helps identify foot abnormalities but also facilitates personalized treatment and pre...
Foot Imaging, Three-Dimensional Diabetic Foot Humans Deep Learning
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Construction and validation of a deep learning-based diagnostic model for segmentation and classification of diabetic foot.

Frontiers in endocrinology Apr 9, 2025
OBJECTIVE: This study aims to conduct an in-depth analysis of diabetic foot ulcer (DFU) images using deep learning models, achieving automated segmentation and classification of the wounds, with the goal of exploring the application of artificial int...
Diabetic Foot Male Humans Deep Learning Female Image Processing, Computer-Assisted
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Establishing a clinical prediction model for diabetic foot ulcers in type 2 diabetic patients with lower extremity arteriosclerotic occlusion using machine learning.

Scientific reports Apr 5, 2025
The burden of diabetic foot ulcers (DFU) is exacerbated in diabetic patients with concomitant arteriosclerotic occlusion disease (ASO) in the lower extremities, who experience more severe symptoms and poorer prognoses. The study aims to develop a pre...
Algorithms Female Aged Male Middle Aged ROC Curve Humans Machine Learning Arterial Occlusive Diseases Lower Extremity Diabetic Foot Arteriosclerosis Diabetes Mellitus, Type 2 Nomograms
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An interpreting machine learning models to predict amputation risk in patients with diabetic foot ulcers: a multi-center study.

Frontiers in endocrinology Mar 25, 2025
BACKGROUND: Diabetic foot ulcers (DFUs) constitute a significant complication among individuals with diabetes and serve as a primary cause of nontraumatic lower-extremity amputation (LEA) within this population. We aimed to develop machine learning (...
Aged Male Middle Aged Amputation, Surgical Risk Assessment Female Humans Risk Factors ROC Curve Machine Learning Diabetic Foot Prognosis Retrospective Studies
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Machine learning-based risk prediction model for neuropathic foot ulcers in patients with diabetic peripheral neuropathy.

Journal of diabetes investigation Mar 21, 2025
BACKGROUND: Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes, marked by symptoms like hyperalgesia, numbness, and swelling that impair quality of life. Nerve conduction abnormalities in DPN significantly increase the ...
Risk Assessment China Diabetic Foot Diabetic Neuropathies Aged Male Middle Aged Female Risk Factors Humans Machine Learning Algorithms Prognosis Retrospective Studies
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