AIMC Topic: Diazepam

Clear Filters Showing 1 to 5 of 5 articles

Maturation of GABAergic signalling times the opening of a critical period in Drosophila melanogaster.

Scientific reports
Critical periods (CPs) during the development of neural networks are widely documented. Activity manipulation during open CPs leads to debilitating effects to the mature neural network. Detailed understanding of the contribution of CPs to network dev...

Development and applications of a machine learning model for an in-depth analysis of pentylenetetrazol-induced seizure-like behaviors in adult zebrafish.

Neuroscience
Epilepsy, a neurological disorder causing recurring seizures, is often studied in zebrafish by exposing animals to pentylenetetrazol (PTZ), which induces clonic- and tonic-like behaviors. While adult zebrafish seizure-like behaviors are well characte...

Predicting drug release from diazepam FDM printed tablets using deep learning approach: Influence of process parameters and tablet surface/volume ratio.

International journal of pharmaceutics
The aim of this study was to apply artificial neural networks as deep learning tools in establishing a model for understanding and prediction of diazepam release from fused deposition modeling (FDM) printed tablets. Diazepam printed tablets of variou...

Region-specific modulation and predictive potential of the oscillatory dynamics in an ex vivo model of ictogenesis in the CA1, CA3 and dentate gyrus.

Neuroscience letters
The hippocampus, including the cornu ammonis (CA) and dentate gyrus (DG) subregions, is a brain area highly susceptible to seizure-like activity (SLA). Most studies conducted in vivo have been performed in a single hippocampal subregion. In our study...

[Determination of diazepam in aquatic products by ultra performance liquid chromatography-tandem mass spectrometry with pass-through solid phase extraction].

Se pu = Chinese journal of chromatography
A method was developed for the determination of diazepam in aquatic products by pass-through solid phase extraction-ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The analyte was extracted with acetonitrile directly an...