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Receptors, GABA-A

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In Silico Prediction of Gamma-Aminobutyric Acid Type-A Receptors Using Novel Machine-Learning-Based SVM and GBDT Approaches.

BioMed research international 27579307
Gamma-aminobutyric acid type-A receptors (GABAARs) belong to multisubunit membrane spanning ligand-gated ion channels (LGICs) which act as the principal mediators of rapid inhibitory synaptic transmission in the human brain. Therefore, the category p...
Algorithms Amino Acid Motifs Amino Acids Brain Computational Biology Computer Simulation Databases, Protein Decision Making Decision Trees Humans Ligands Machine Learning Models, Statistical Receptors, GABA-A Reproducibility of Results Support Vector Machine
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γ-Aminobutyric Acid Type A Receptor Potentiation Inhibits Learning in a Computational Network Model.

Anesthesiology 29664887
BACKGROUND: Propofol produces memory impairment at concentrations well below those abolishing consciousness. Episodic memory, mediated by the hippocampus, is most sensitive. Two potentially overlapping scenarios may explain how γ-aminobutyric acid re...
Anesthetics, Intravenous Computer Simulation GABA-A Receptor Agonists Hippocampus Humans Learning Memory Neural Networks, Computer Neuronal Plasticity Propofol Receptors, GABA-A
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Application of Single-Nucleotide Polymorphisms in the Diagnosis of Autism Spectrum Disorders: A Preliminary Study with Artificial Neural Networks.

Journal of molecular neuroscience : MN 30937628
Autism spectrum disorder (ASD) includes different neurodevelopmental disorders characterized by deficits in social communication, and restricted, repetitive patterns of behavior, interests or activities. Based on the importance of early diagnosis for...
Autism Spectrum Disorder Child Deep Learning Female Genetic Testing Humans Male Polymorphism, Single Nucleotide Receptors, GABA-A Receptors, Metabotropic Glutamate Sensitivity and Specificity Synaptosomal-Associated Protein 25
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