AIMC Topic: Disease

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The assessment of efficient representation of drug features using deep learning for drug repositioning.

BMC bioinformatics
BACKGROUND: De novo drug discovery is a time-consuming and expensive process. Nowadays, drug repositioning is utilized as a common strategy to discover a new drug indication for existing drugs. This strategy is mostly used in cases with a limited num...

Artificial Intelligence Meets Chinese Medicine.

Chinese journal of integrative medicine
As an interdisciplinary subject of medicine and artificial intelligence, intelligent diagnosis and treatment has received extensive attention. The standardization of Chinese medicine (CM) diagnosis has been always a bottleneck in the modernization an...

MLMDA: a machine learning approach to predict and validate MicroRNA-disease associations by integrating of heterogenous information sources.

Journal of translational medicine
BACKGROUND: Emerging evidences show that microRNA (miRNA) plays an important role in many human complex diseases. However, considering the inherent time-consuming and expensive of traditional in vitro experiments, more and more attention has been pai...

ROBOT: A Tool for Automating Ontology Workflows.

BMC bioinformatics
BACKGROUND: Ontologies are invaluable in the life sciences, but building and maintaining ontologies often requires a challenging number of distinct tasks such as running automated reasoners and quality control checks, extracting dependencies and appl...

Chemical-induced disease relation extraction via attention-based distant supervision.

BMC bioinformatics
BACKGROUND: Automatically understanding chemical-disease relations (CDRs) is crucial in various areas of biomedical research and health care. Supervised machine learning provides a feasible solution to automatically extract relations between biomedic...

PhenPath: a tool for characterizing biological functions underlying different phenotypes.

BMC genomics
BACKGROUND: Many diseases are associated with complex patterns of symptoms and phenotypic manifestations. Parsimonious explanations aim at reconciling the multiplicity of phenotypic traits with the perturbation of one or few biological functions. For...

Automatic classification of free-text medical causes from death certificates for reactive mortality surveillance in France.

International journal of medical informatics
BACKGROUND: Mortality surveillance is of fundamental importance to public health surveillance. The real-time recording of death certificates, thanks to Electronic Death Registration System (EDRS), provides valuable data for reactive mortality surveil...

Development of Big Data Predictive Analytics Model for Disease Prediction using Machine learning Technique.

Journal of medical systems
Now days, health prediction in modern life becomesvery much essential. Big data analysis plays a crucial role to predict future status of healthand offerspreeminenthealth outcome to people. Heart disease is a prevalent disease cause's death around th...

Enhancing ontology-driven diagnostic reasoning with a symptom-dependency-aware Naïve Bayes classifier.

BMC bioinformatics
BACKGROUND: Ontology has attracted substantial attention from both academia and industry. Handling uncertainty reasoning is important in researching ontology. For example, when a patient is suffering from cirrhosis, the appearance of abdominal vein v...