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Drug Hypersensitivity

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Non-ionic iodinated contrast media related immediate reactions: A mechanism study of 27 patients.

Legal medicine (Tokyo, Japan)
The underlying mechanism of non-ionic iodinated contrast media-related immediate reactions was evaluated in this study. Patients presenting at least grade II immediate reactions after non-ionic iodinated contrast media injection were enrolled. Basoph...

Artificial intelligence and the potential for perioperative delabeling of penicillin allergies for neurosurgery inpatients.

British journal of neurosurgery
PURPOSE OF THE ARTICLE: Patients with penicillin allergy labels are more likely to have postoperative wound infections. When penicillin allergy labels are interrogated, a significant number of individuals do not have penicillin allergies and may be d...

Predicting Penicillin Allergy: A United States Multicenter Retrospective Study.

The journal of allergy and clinical immunology. In practice
BACKGROUND: Using the reaction history in logistic regression and machine learning (ML) models to predict penicillin allergy has been reported based on non-US data.

Improving the performance of machine learning penicillin adverse drug reaction classification with synthetic data and transfer learning.

Internal medicine journal
BACKGROUND: Machine learning may assist with the identification of potentially inappropriate penicillin allergy labels. Strategies to improve the performance of existing models for this task include the use of additional training data, synthetic data...

Predictive models and applicability of artificial intelligence-based approaches in drug allergy.

Current opinion in allergy and clinical immunology
PURPOSE OF REVIEW: Drug allergy is responsible for a huge burden on public healthcare systems, representing in some instances a threat for patient's life. Diagnosis is complex due to the heterogeneity of clinical phenotypes and mechanisms involved, t...