AIMC Topic: Drug Labeling

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Evaluation of Natural Language Processing (NLP) systems to annotate drug product labeling with MedDRA terminology.

Journal of biomedical informatics
INTRODUCTION: The FDA Adverse Event Reporting System (FAERS) is a primary data source for identifying unlabeled adverse events (AEs) in a drug or biologic drug product's postmarketing phase. Many AE reports must be reviewed by drug safety experts to ...

DrugSemantics: A corpus for Named Entity Recognition in Spanish Summaries of Product Characteristics.

Journal of biomedical informatics
For the healthcare sector, it is critical to exploit the vast amount of textual health-related information. Nevertheless, healthcare providers have difficulties to benefit from such quantity of data during pharmacotherapeutic care. The problem is tha...

Overlap in drug-disease associations between clinical practice guidelines and drug structured product label indications.

Journal of biomedical semantics
BACKGROUND: Clinical practice guidelines (CPGs) recommend pharmacologic treatments for clinical conditions, and drug structured product labels (SPLs) summarize approved treatment indications. Both resources are intended to promote evidence-based medi...

Automatic Classification of Structured Product Labels for Pregnancy Risk Drug Categories, a Machine Learning Approach.

AMIA ... Annual Symposium proceedings. AMIA Symposium
With regular expressions and manual review, 18,342 FDA-approved drug product labels were processed to determine if the five standard pregnancy drug risk categories were mentioned in the label. After excluding 81 drugs with multiple-risk categories, 8...

AI-Assisted Application for Pediatric Drug Dosing.

Studies in health technology and informatics
Technology in the medical field is continuously advancing due to its numerous subdomains and the ever-growing medical needs of people. Information systems have become integral to doctors' daily routines in patient care, offering flexibility and suppo...

Knowledge-guided generative artificial intelligence for automated taxonomy learning from drug labels.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVES: To automatically construct a drug indication taxonomy from drug labels using generative Artificial Intelligence (AI) represented by the Large Language Model (LLM) GPT-4 and real-world evidence (RWE).

Using Supervised Learning Methods to Develop a List of Prescription Medications of Greatest Concern during Pregnancy.

Maternal and child health journal
INTRODUCTION: Women and healthcare providers lack adequate information on medication safety during pregnancy. While resources describing fetal risk are available, information is provided in multiple locations, often with subjective assessments of ava...

Searches for randomized controlled trials of drugs in MEDLINE and EMBASE using only generic drug names compared with searches applied in current practice in systematic reviews.

Research synthesis methods
BACKGROUND: It is unclear which terms should be included in bibliographic searches for randomized controlled trials (RCTs) of drugs, and identifying relevant drug terms can be extremely laborious. The aim of our analysis was to determine whether a bi...

Augmented Reality: Real-Time Information Concerning Medication Consumed by a Patient.

Studies in health technology and informatics
This paper describes a mobile prototype capable of recognizing characters from a photograph of a medication package. The prototype was built to work on the iOS platform and was developed using Objective-C and C programming languages. The prototype, c...