AIMC Topic: Drug Repositioning
Clear Filters Showing 71 to 80 of 270 articles
A novel efficient drug repurposing framework through drug-disease association data integration using convolutional neural networks.
BMC bioinformatics
Nov 22, 2023
Drug repurposing is an exciting field of research toward recognizing a new FDA-approved drug target for the treatment of a specific disease. It has received extensive attention regarding the tedious, time-consuming, and highly expensive procedure wit...
Repositioning of Ureteropelvic Junction in Robot-assisted Laparoscopic Pyeloplasty.
Urology
Nov 3, 2023
OBJECTIVE: To describe the technique of ureteropelvic junction (UPJ) repositioning in robot-assisted dismembered pyeloplasty as a modified approach during which the UPJ is brought to a new location to facilitate the anastomosis.
Protocol to implement a computational pipeline for biomedical discovery based on a biomedical knowledge graph.
STAR protocols
Oct 25, 2023
Biomedical knowledge graphs (BKGs) provide a new paradigm for managing abundant biomedical knowledge efficiently. Today's artificial intelligence techniques enable mining BKGs to discover new knowledge. Here, we present a protocol for implementing a ...
Uncovering hidden therapeutic indications through drug repurposing with graph neural networks and heterogeneous data.
Artificial intelligence in medicine
Oct 21, 2023
Drug repurposing has gained the attention of many in the recent years. The practice of repurposing existing drugs for new therapeutic uses helps to simplify the drug discovery process, which in turn reduces the costs and risks that are associated wit...
EGeRepDR: An enhanced genetic-based representation learning for drug repurposing using multiple biomedical sources.
Journal of biomedical informatics
Oct 18, 2023
MOTIVATION: Drug repurposing (DR) is an imminent approach for identifying novel therapeutic indications for the available drugs and discovering novel drugs for previously untreatable diseases. Nowadays, DR has major attention in the pharmaceutical in...
Multi-Label Classification With Dual Tail-Node Augmentation for Drug Repositioning.
IEEE/ACM transactions on computational biology and bioinformatics
Oct 9, 2023
Due to the lengthy and costly process of new drug discovery, increasing attention has been paid to drug repositioning, i.e., identifying new drug-disease associations. Current machine learning methods for drug repositioning mainly leverage matrix fac...
Discovering the mechanism of action of drugs with a sparse explainable network.
EBioMedicine
Aug 24, 2023
BACKGROUND: Although Deep Neural Networks (DDNs) have been successful in predicting the efficacy of cancer drugs, the lack of explainability in their decision-making process is a significant challenge. Previous research proposed mimicking the Gene On...
Cheminformatics and machine learning approaches for repurposing anti-viral compounds against monkeypox virus thymidylate kinase.
Molecular diversity
Aug 2, 2023
One of the emerging epidemic concerns is Monkeypox disease which is spreading globally. This disease is caused by the monkeypox virus (MPXV), with an increasing global incidence with an outbreak in 2022. One of the novel targets for monkeypox disease...
Artificial intelligence-assisted repurposing of lubiprostone alleviates tubulointerstitial fibrosis.
Translational research : the journal of laboratory and clinical medicine
Aug 2, 2023
Tubulointerstitial fibrosis (TIF) is the most prominent cause which leads to chronic kidney disease (CKD) and end-stage renal failure. Despite extensive research, there have been many clinical trial failures, and there is currently no effective treat...
Exploring the potential of FDA approved anti-diabetic drugs for repurposing against COVID-19: a core combination of multiple computational strategies and integrated artificial intelligence.
Journal of biomolecular structure & dynamics
Jul 16, 2023
The latest variant of coronavirus is omicron. The World Health Organization (WHO) designated variation 'B.1.1.529' named omicron as a variant of concern (VOC) on 26 November 2021. By September 2020, it will have infected over 16 million patients and ...
Stay Ahead of Medical AI
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 30978
- Neural Networks, Computer 29696
- Algorithms 26813
- Deep Learning 26324
- Artificial Intelligence 24267
- Robotics 13307
- Image Processing, Computer-Assisted 9512
- Retrospective Studies 9097
- Magnetic Resonance Imaging 6173
- Reproducibility of Results 5589
- Tomography, X-Ray Computed 4765
- Support Vector Machine 4678
- Computational Biology 4229
- Brain 4045
- Computer Simulation 3877
Recent Journals
- Scientific reports 5865
- Sensors (Basel, Switzerland) 4794
- PloS one 4011
- Neural networks : the official journal of the International Neural Network Society 2928
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1839
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1278
- IEEE journal of biomedical and health informatics 1129
- Journal of chemical information and modeling 994
- Nature communications 938
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 861
- Briefings in bioinformatics 850
- IEEE transactions on neural networks and learning systems 823