AIMC Topic: Drug Resistant Epilepsy
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Localizing seizure onset zones in surgical epilepsy with neurostimulation deep learning.
Journal of neurosurgery
Sep 23, 2022
OBJECTIVE: In drug-resistant temporal lobe epilepsy, automated tools for seizure onset zone (SOZ) localization that use brief interictal recordings could supplement presurgical evaluations and improve care. Thus, the authors sought to localize SOZs b...
SEEG-Net: An explainable and deep learning-based cross-subject pathological activity detection method for drug-resistant epilepsy.
Computers in biology and medicine
Jun 29, 2022
OBJECTIVE: Precise preoperative evaluation of drug-resistant epilepsy (DRE) requires accurate analysis of invasive stereoelectroencephalography (SEEG). With the tremendous breakthrough of Artificial intelligence (AI), previous studies can help clinic...
Deep learning resting state functional magnetic resonance imaging lateralization of temporal lobe epilepsy.
Epilepsia
Apr 1, 2022
OBJECTIVE: Localization of focal epilepsy is critical for surgical treatment of refractory seizures. There remains a great need for noninvasive techniques to localize seizures for surgical decision-making. We investigate the use of deep learning usin...
Robot-assisted, real-time, MRI-guided laser interstitial thermal therapy for pediatric patients with hypothalamic hamartoma: surgical technique, pitfalls, and initial results.
Journal of neurosurgery. Pediatrics
Mar 25, 2022
OBJECTIVE: Real-time, MRI-guided laser interstitial thermal therapy (MRgLITT) has been reported as a safe and effective technique for the treatment of epileptogenic foci in children and adults. After the recent approval of MRgLITT by the European Med...
A neuromorphic spiking neural network detects epileptic high frequency oscillations in the scalp EEG.
Scientific reports
Feb 2, 2022
Interictal High Frequency Oscillations (HFO) are measurable in scalp EEG. This development has aroused interest in investigating their potential as biomarkers of epileptogenesis, seizure propensity, disease severity, and treatment response. The deman...
Drug Resistant Epilepsy
Epilepsies, Partial
Artifacts
Brain Waves
Child, Preschool
Child
Treatment Outcome
Predictive Value of Tests
Electroencephalography
Signal Processing, Computer-Assisted
Humans
Adolescent
Neural Networks, Computer
Wearable Electronic Devices
Brain
Time Factors
Female
Male
Reproducibility of Results
Infant
A simulation study to investigate the use of concentric tube robots for epilepsy surgery.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Jan 27, 2022
PURPOSE: Patients with pharmacoresistant refractory epilepsy may require epilepsy surgery to prevent future seizure occurrences. Conventional surgery consists of a large craniotomy with straight rigid tools with associated outcomes of morbidity, larg...
Electroclinical spectrum of generalized paroxysmal fast activity in adults without epileptic encephalopathy.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Jan 16, 2022
INTRODUCTION: Generalized paroxysmal fast activity (GPFA) is a rare and underreported EEG pattern known to be related to epileptic encephalopathy. We aimed to investigate the electroclinical spectrum of GPFA along with other atypical EEG features in ...
Robot-assisted stereoelectroencephalography in young children: technical challenges and considerations.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Oct 30, 2021
Robot-assisted stereoelectroencephalography (sEEG) is frequently employed to localize epileptogenic zones in patients with medically refractory epilepsy (MRE). Its methodology is well described in adults, but less so in children. Given the limited in...
Neurosurgical robot-assistant stereoelectroencephalography system: Operability and accuracy.
Brain and behavior
Sep 14, 2021
BACKGROUND: Fine operation has been an eternal topic in neurosurgery. There were many problems in functional neurosurgery field with high precision requirements. Our study aims to explore the operability, accuracy and postoperative effect of robot-as...
Neuromagnetic high frequency spikes are a new and noninvasive biomarker for localization of epileptogenic zones.
Seizure
May 4, 2021
OBJECTIVE: One barrier hindering high frequency brain signals (HFBS, >80 Hz) from wide clinical applications is that the brain generates both pathological and physiological HFBS. This study was to find specific biomarkers for localizing epileptogenic...
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