AIMC Topic: Dry Eye Syndromes

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Ocular Distribution and Pharmacokinetics of Lifitegrast in Pigmented Rabbits and Mass Balance in Beagle Dogs.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
PURPOSE: Lifitegrast is approved in the United States for the treatment of dry eye disease (DED). We assessed lifitegrast's ocular distribution/pharmacokinetic profile in rabbits, and C-lifitegrast mass balance/excretion in dogs.

[Advancements of artificial intelligence in dry eye].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
With the continuous evolution of computer technology and the surging advent of the big data era, artificial intelligence (AI) has already manifested extremely broad application prospects. Medical AI, like a capable assistant, can help doctors make mo...

[Vigorously advancing the application of AI in the diagnosis and treatment of ocular surface and tear diseases].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
Ocular surface and tear diseases are among the most common and significant ocular conditions affecting eye health. In recent years, research and clinical diagnosis and treatment of ocular surface and tear diseases have rapidly developed in China, but...

[Practical Application of Intelligent Vision Measurement System Based on Deep Learning].

Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation
To comprehensively assess the true visual function of clinical dry eye patients and the comprehensive impact of blinking characteristics on functional vision of the human eye, an intelligent vision measurement system has been designed and developed t...

Enhancing Meibography Image Analysis Through Artificial Intelligence-Driven Quantification and Standardization for Dry Eye Research.

Translational vision science & technology
PURPOSE: This study enhances Meibomian gland (MG) infrared image analysis in dry eye (DE) research through artificial intelligence (AI). It is comprised of two main stages: automated eyelid detection and tarsal plate segmentation to standardize meibo...

Visual analysis of autoimmune dry eye studies based on bibliometrics.

Medicine
BACKGROUND: Dry eye is a chronic ocular surface disease caused by the instability of tear film or the imbalance of the ocular surface microenvironment which can lead to a diverse range of ocular discomfort symptoms. At present, the relevant mechanism...

Unsupervised Learning Based on Meibography Enables Subtyping of Dry Eye Disease and Reveals Ocular Surface Features.

Investigative ophthalmology & visual science
PURPOSE: This study aimed to establish an image-based classification that can reveal the clinical characteristics of patients with dry eye using unsupervised learning methods.

[Infrared Imaging Meibomian Gland Segmentation System Based on Deep Learning].

Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation
In order to better assist doctors in the diagnosis of dry eye and improve the ability of ophthalmologists to recognize the condition of meibomian gland, a meibomian gland image segmentation and enhancement method based on Mobile-U-Net network was pro...

Impact of Incomplete Blinking Analyzed Using a Deep Learning Model With the Keratograph 5M in Dry Eye Disease.

Translational vision science & technology
PURPOSE: To establish a deep learning model (DLM) for blink analysis, and investigate whether blink video frame sampling rate influences the accuracy of analysis.