PURPOSE: Infiltration of activated dendritic cells and inflammatory cells in cornea represents an important marker for defining corneal inflammation. Deep transfer learning has presented a promising potential and is gaining more importance in compute...
PURPOSE: To report a multidisease deep learning diagnostic network (MDDN) of common corneal diseases: dry eye syndrome (DES), Fuchs endothelial dystrophy (FED), and keratoconus (KCN) using anterior segment optical coherence tomography (AS-OCT) images...
Archivos de la Sociedad Espanola de Oftalmologia
May 20, 2019
OBJECTIVE: Because of high variability, tear film osmolarity measures have been questioned in dry eye assessment. Understanding the origin of such variability would aid data interpretation. This study aims to evaluate osmolarity variability in a clin...
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Dec 21, 2017
PURPOSE: Lifitegrast is approved in the United States for the treatment of dry eye disease (DED). We assessed lifitegrast's ocular distribution/pharmacokinetic profile in rabbits, and C-lifitegrast mass balance/excretion in dogs.
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
Feb 14, 2025
With the continuous evolution of computer technology and the surging advent of the big data era, artificial intelligence (AI) has already manifested extremely broad application prospects. Medical AI, like a capable assistant, can help doctors make mo...
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
Feb 14, 2025
Ocular surface and tear diseases are among the most common and significant ocular conditions affecting eye health. In recent years, research and clinical diagnosis and treatment of ocular surface and tear diseases have rapidly developed in China, but...
Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation
Jul 30, 2024
To comprehensively assess the true visual function of clinical dry eye patients and the comprehensive impact of blinking characteristics on functional vision of the human eye, an intelligent vision measurement system has been designed and developed t...
Translational vision science & technology
Jun 3, 2024
PURPOSE: This study enhances Meibomian gland (MG) infrared image analysis in dry eye (DE) research through artificial intelligence (AI). It is comprised of two main stages: automated eyelid detection and tarsal plate segmentation to standardize meibo...
BACKGROUND: Dry eye is a chronic ocular surface disease caused by the instability of tear film or the imbalance of the ocular surface microenvironment which can lead to a diverse range of ocular discomfort symptoms. At present, the relevant mechanism...
Investigative ophthalmology & visual science
Oct 3, 2023
PURPOSE: This study aimed to establish an image-based classification that can reveal the clinical characteristics of patients with dry eye using unsupervised learning methods.
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