AIMC Topic: Esophageal Mucosa
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A spatiotemporal and machine-learning platform facilitates the manufacturing of hPSC-derived esophageal mucosa.
Developmental cell
Jan 10, 2025
Human pluripotent stem cell-derived tissue engineering offers great promise for designer cell-based personalized therapeutics, but harnessing such potential requires a deeper understanding of tissue-level interactions. We previously developed a cell ...
A Pilot Study on Automatic Three-Dimensional Quantification of Barrett's Esophagus for Risk Stratification and Therapy Monitoring.
Gastroenterology
Jun 8, 2021
BACKGROUND & AIMS: Barrett's epithelium measurement using widely accepted Prague C&M classification is highly operator dependent. We propose a novel methodology for measuring this risk score automatically. The method also enables quantification of th...
Barrett Esophagus
Automation
Image Interpretation, Computer-Assisted
Esophageal Mucosa
Esophagoscopy
Esophagogastric Junction
Imaging, Three-Dimensional
Predictive Value of Tests
Treatment Outcome
Deep Learning
Pilot Projects
Severity of Illness Index
Humans
Male
Aged
Disease Progression
Risk Assessment
Reproducibility of Results
Risk Factors
Female
Early Esophageal Cancer: A Gastroenterologist's Disease.
Digestive diseases and sciences
Aug 30, 2019
Traditionally, early esophageal cancer (i.e., cancer limited to the mucosa or superficial submucosa) was managed surgically; the gastroenterologist's role was primarily to diagnose the tumor. Over the last decade, advances in endoscopic imaging, abla...
Endoscopic Surveillance of Barrett's Esophagus Using Volumetric Laser Endomicroscopy With Artificial Intelligence Image Enhancement.
Gastroenterology
May 9, 2019
What insights can spatiotemporal esophageal atlases and deep learning bring to engineering the esophageal mucosa?
Developmental cell
May 5, 2025
In this issue of Developmental Cell, Yang et al. present an integrated experimental and computational platform that maps the spatiotemporal development of the human esophagus and predicts key signaling pathways governing epithelial differentiation. T...
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