AIMC Topic: Genetic Engineering

Clear Filters Showing 11 to 20 of 24 articles

Designing Eukaryotic Gene Expression Regulation Using Machine Learning.

Trends in biotechnology Aug 17, 2019
Controlling the expression of genes is one of the key challenges of synthetic biology. Until recently fine-tuned control has been out of reach, particularly in eukaryotes owing to their complexity of gene regulation. With advances in machine learning...
Genetic Engineering Eukaryotic Cells Synthetic Biology Gene Expression Regulation Eukaryota Machine Learning Algorithms Models, Genetic Flow Cytometry Genetic Variation
View on PubMed DOI

EternaBrain: Automated RNA design through move sets and strategies from an Internet-scale RNA videogame.

PLoS computational biology Jun 27, 2019
Emerging RNA-based approaches to disease detection and gene therapy require RNA sequences that fold into specific base-pairing patterns, but computational algorithms generally remain inadequate for these secondary structure design tasks. The Eterna p...
Humans Neural Networks, Computer Algorithms Genetic Engineering Nucleic Acid Conformation Sequence Analysis, RNA Crowdsourcing Internet Video Games RNA
View on PubMed DOI

Artificial intelligence, robotics and cyborgs: The future of research and technological development in ophthalmology.

Archivos de la Sociedad Espanola de Oftalmologia May 27, 2019
Robotics Ophthalmology Inventions Forecasting Computer Simulation Big Data Biomedical Engineering Bionics Genetic Engineering Humans Artificial Intelligence
View on PubMed DOI

Standardizing Automated DNA Assembly: Best Practices, Metrics, and Protocols Using Robots.

SLAS technology Feb 15, 2019
The advancement of synthetic biology requires the ability to create new DNA sequences to produce unique behaviors in biological systems. Automation is increasingly employed to carry out well-established assembly methods of DNA fragments in a multiple...
Synthetic Biology Practice Guidelines as Topic Cloning, Molecular Genetic Engineering Automation, Laboratory Robotics DNA
View on PubMed DOI

Deep learning to predict the lab-of-origin of engineered DNA.

Nature communications Aug 7, 2018
Genetic engineering projects are rapidly growing in scale and complexity, driven by new tools to design and construct DNA. There is increasing concern that widened access to these technologies could lead to attempts to construct cells for malicious i...
Plasmids Genetic Engineering Deep Learning Image Processing, Computer-Assisted DNA Bayes Theorem Neural Networks, Computer Mutation Software Synthetic Biology
View on PubMed DOI

Digital-to-biological converter for on-demand production of biologics.

Nature biotechnology May 29, 2017
Manufacturing processes for biological molecules in the research laboratory have failed to keep pace with the rapid advances in automization and parellelization. We report the development of a digital-to-biological converter for fully automated, vers...
High-Throughput Nucleotide Sequencing Synthetic Biology Equipment Failure Analysis Genetic Engineering Biopolymers Biological Products Robotics Equipment Design
View on PubMed DOI

Biological standards for the Knowledge-Based BioEconomy: What is at stake.

New biotechnology May 4, 2017
The contribution of life sciences to the Knowledge-Based Bioeconomy (KBBE) asks for the transition of contemporary, gene-based biotechnology from being a trial-and-error endeavour to becoming an authentic branch of engineering. One requisite to this ...
Knowledge Bases Genetic Engineering Synthetic Biology Biotechnology Economic Development
View on PubMed DOI

A Knowledge-Based System for Display and Prediction of O-Glycosylation Network Behaviour in Response to Enzyme Knockouts.

PLoS computational biology Apr 7, 2016
O-linked glycosylation is an important post-translational modification of mucin-type protein, changes to which are important biomarkers of cancer. For this study of the enzymes of O-glycosylation, we developed a shorthand notation for representing Ga...
CHO Cells Glycosyltransferases Humans Cricetulus Computer Simulation Genetic Engineering Mucins Models, Biological Metabolic Networks and Pathways Animals Computational Biology Terminology as Topic Polysaccharides Glycosylation Gene Knockout Techniques Knowledge Bases Protein Processing, Post-Translational
View on PubMed DOI

Exploring Host-Microbiome Interactions using an in Silico Model of Biomimetic Robots and Engineered Living Cells.

Scientific reports Jul 16, 2015
The microbiome's underlying dynamics play an important role in regulating the behavior and health of its host. In order to explore the details of these interactions, we created an in silico model of a living microbiome, engineered with synthetic biol...
Host-Pathogen Interactions Models, Biological Cells Computer Simulation Genetic Engineering Microbiota Robotics Biomimetics
View on PubMed DOI

[Artificial intelligence-assisted design, mining, and modification of CRISPR-Cas systems].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology Mar 25, 2025
With the rapid advancement of synthetic biology, CRISPR-Cas systems have emerged as a powerful tool for gene editing, demonstrating significant potential in various fields, including medicine, agriculture, and industrial biotechnology. This review co...
Artificial Intelligence Gene Editing Genetic Engineering CRISPR-Cas Systems RNA, Guide, CRISPR-Cas Systems Data Mining Synthetic Biology
View on PubMed DOI
Popular Topics
Recent Journals