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Glaucoma

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The role of neuroinflammation in the pathogenesis of glaucoma neurodegeneration.

Progress in brain research
The chapter is a review enclosed in the volume "Glaucoma: A pancitopatia of the retina and beyond." No cure exists for glaucoma. Knowledge on the molecular and cellular alterations underlying glaucoma neurodegeneration (GL-ND) includes innovative and...

Artificial intelligence and deep learning in glaucoma: Current state and future prospects.

Progress in brain research
Over the past few years, there has been an unprecedented and tremendous excitement for artificial intelligence (AI) research in the field of Ophthalmology; this has naturally been translated to glaucoma-a progressive optic neuropathy characterized by...

A Review of Deep Learning for Screening, Diagnosis, and Detection of Glaucoma Progression.

Translational vision science & technology
UNLABELLED: Because of recent advances in computing technology and the availability of large datasets, deep learning has risen to the forefront of artificial intelligence, with performances that often equal, or sometimes even exceed, those of human s...

Deep learning model to predict visual field in central 10° from optical coherence tomography measurement in glaucoma.

The British journal of ophthalmology
BACKGROUND/AIM: To train and validate the prediction performance of the deep learning (DL) model to predict visual field (VF) in central 10° from spectral domain optical coherence tomography (SD-OCT).

Effect of color information on the diagnostic performance of glaucoma in deep learning using few fundus images.

International ophthalmology
PURPOSE: The purpose of this study was to evaluate the accuracy of the convolutional neural network (CNN) model in glaucoma identification with three primary colors (red, green, blue; RGB) and split color channels using fundus photographs with a smal...

Explaining the Rationale of Deep Learning Glaucoma Decisions with Adversarial Examples.

Ophthalmology
PURPOSE: To illustrate what is inside the so-called black box of deep learning models (DLMs) so that clinicians can have greater confidence in the conclusions of artificial intelligence by evaluating adversarial explanation on its ability to explain ...

WGAN domain adaptation for the joint optic disc-and-cup segmentation in fundus images.

International journal of computer assisted radiology and surgery
PURPOSE: The cup-to-disc ratio (CDR), a clinical metric of the relative size of the optic cup to the optic disc, is a key indicator of glaucoma, a chronic eye disease leading to loss of vision. CDR can be measured from fundus images through the segme...

AxoNet: A deep learning-based tool to count retinal ganglion cell axons.

Scientific reports
In this work, we develop a robust, extensible tool to automatically and accurately count retinal ganglion cell axons in optic nerve (ON) tissue images from various animal models of glaucoma. We adapted deep learning to regress pixelwise axon count de...