AIMC Topic: Hepacivirus

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Chronic kidney disease in Hepatitis C and its association with liver cirrhosis and viral load: Revealing the importance of hematuria.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia Jan 1, 2021
Hepatitis C virus (HCV) contributed as a risk factor for chronic kidney disease (CKD). Many studies only showed it associated with estimated glomerular filtration rate (eGFR) reduction and albuminuria, but none revealed hematuria data. Besides, liver...
Viral Load Hepatitis C Risk Factors Liver Cirrhosis Cross-Sectional Studies Hematuria Glomerular Filtration Rate Humans Renal Insufficiency, Chronic Male Albuminuria Female Hepacivirus
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Assisting the Non-invasive Diagnosis of Liver Fibrosis Stages using Machine Learning Methods.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Jul 1, 2020
Fibrosis is a significant indication of chronic liver diseases often due to hepatitis C Virus. It is becoming a global concern as a result of the rapid increase in the number of HCV infected patients, the high cost and flaws associated with the asses...
Logistic Models Liver Cirrhosis Hepacivirus Humans Neural Networks, Computer Machine Learning
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[A real-world study of paritaprevir/ritonavir-ombitasvir combined with dasabuvir in the treatment of genotype 1b chronic hepatitis C].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology Dec 20, 2018
To recognize the efficacy and safety of paritaprevir/ritonavir-ombitasvir combined with dasabuvir (OBV/PTV/RTV+DSV) in the treatment of genotype 1b chronic hepatitis C. Patients with genotype 1b chronic hepatitis C who were admitted to the People's...
Male Uracil Middle Aged China Ribavirin 2-Naphthylamine Antiviral Agents Hepatitis C, Chronic Genotype Valine Treatment Outcome Humans Proline Anilides Carbamates Ritonavir Cyclopropanes Lactams, Macrocyclic Drug Therapy, Combination Sulfonamides Macrocyclic Compounds Hepacivirus
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WAITING DAAS LIST MORTALITY IMPACT IN HCV CIRRHOTIC PATIENTS.

Arquivos de gastroenterologia Jan 1, 2018
BACKGROUND: The infection for the hepatitis C virus (HCV) is a leading cause of liver-related morbidity and mortality through its evolution to liver cirrhosis, end-stage liver complications and hepatocellular carcinoma. Currently, the new drugs for t...
Waiting Lists Hepatitis C, Chronic Liver Cirrhosis Hepacivirus Humans Incidence Risk Factors Prospective Studies Liver Neoplasms Male Female Antiviral Agents Middle Aged
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Association of ATP-Binding Cassette Transporter (ABC) Gene Polymorphisms with Viral Load in Patients with Genotype 1 Hepatitis C Virus Infection.

Clinical laboratory Sep 1, 2016
BACKGROUND: ATP-binding cassette transporters (ABC) gene polymorphisms are associated with various biological functions, including hepatitis C virus (HCV) infection. This study aims to explore the impact of ABC transporters polymorphisms on HCV viral...
ATP Binding Cassette Transporter, Subfamily B, Member 1 Hepacivirus Hepatitis C, Chronic Interleukins Neoplasm Proteins ATP Binding Cassette Transporter, Subfamily B ATP Binding Cassette Transporter, Subfamily B, Member 11 ATP Binding Cassette Transporter, Subfamily G, Member 2 Gene Frequency ATP-Binding Cassette Transporters ATP Binding Cassette Transporter 1 Male Middle Aged Viral Load Polymorphism, Single Nucleotide Genotype Lipoproteins Humans Female ATP Binding Cassette Transporter, Subfamily G, Member 5
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[Characterization of Serial Passage of 1b/2a Chimera Hepatitis C Virus Cell Culture System Carrying Envelope E1E2 Coding Gene from Hebei Strain of China].

Bing du xue bao = Chinese journal of virology Nov 1, 2015
To character a novel chimera(1b/2a) hepatitis C virus cell culture (HCVcc) system carrying envelope E1E2 coding gene from Hebei strain of China, chimera HCVcc (cHCVcc) was developed from Huh7.5-CD81 cells after transfection with in vitro transcribed ...
Hepatitis C China Viral Envelope Proteins Humans Cell Line Serial Passage Hepacivirus
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Classification models of HCV NS3 protease inhibitors based on support vector machine (SVM).

Combinatorial chemistry & high throughput screening Jan 1, 2015
Inhibition of the hepatitis C virus (HCV) non-structural protein 3 (NS3) serine protease by molecule inhibitors is an attractive strategy for the treatment of hepatitis C. We built four classification models based on a dataset of 413 HCV NS3 protease...
Viral Nonstructural Proteins Protease Inhibitors Databases, Pharmaceutical Hepacivirus Hepatitis C Quantitative Structure-Activity Relationship Humans Molecular Docking Simulation Support Vector Machine
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