AIMC Topic: Hepacivirus

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Assisting the Non-invasive Diagnosis of Liver Fibrosis Stages using Machine Learning Methods.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Jul 1, 2020
Fibrosis is a significant indication of chronic liver diseases often due to hepatitis C Virus. It is becoming a global concern as a result of the rapid increase in the number of HCV infected patients, the high cost and flaws associated with the asses...
Humans Logistic Models Neural Networks, Computer Liver Cirrhosis Machine Learning Hepacivirus
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[A real-world study of paritaprevir/ritonavir-ombitasvir combined with dasabuvir in the treatment of genotype 1b chronic hepatitis C].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology Dec 20, 2018
To recognize the efficacy and safety of paritaprevir/ritonavir-ombitasvir combined with dasabuvir (OBV/PTV/RTV+DSV) in the treatment of genotype 1b chronic hepatitis C. Patients with genotype 1b chronic hepatitis C who were admitted to the People's...
Proline Ritonavir Hepatitis C, Chronic Valine Drug Therapy, Combination Sulfonamides Hepacivirus Treatment Outcome Humans Cyclopropanes 2-Naphthylamine China Lactams, Macrocyclic Uracil Antiviral Agents Male Anilides Genotype Macrocyclic Compounds Middle Aged Carbamates Ribavirin
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WAITING DAAS LIST MORTALITY IMPACT IN HCV CIRRHOTIC PATIENTS.

Arquivos de gastroenterologia Jan 1, 2018
BACKGROUND: The infection for the hepatitis C virus (HCV) is a leading cause of liver-related morbidity and mortality through its evolution to liver cirrhosis, end-stage liver complications and hepatocellular carcinoma. Currently, the new drugs for t...
Waiting Lists Hepatitis C, Chronic Male Liver Cirrhosis Middle Aged Hepacivirus Female Humans Incidence Liver Neoplasms Risk Factors Prospective Studies Antiviral Agents
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Association of ATP-Binding Cassette Transporter (ABC) Gene Polymorphisms with Viral Load in Patients with Genotype 1 Hepatitis C Virus Infection.

Clinical laboratory Sep 1, 2016
BACKGROUND: ATP-binding cassette transporters (ABC) gene polymorphisms are associated with various biological functions, including hepatitis C virus (HCV) infection. This study aims to explore the impact of ABC transporters polymorphisms on HCV viral...
ATP-Binding Cassette Transporters ATP Binding Cassette Transporter 1 ATP Binding Cassette Transporter, Subfamily B Hepatitis C, Chronic Gene Frequency ATP Binding Cassette Transporter, Subfamily G, Member 5 ATP Binding Cassette Transporter, Subfamily B, Member 11 ATP Binding Cassette Transporter, Subfamily G, Member 2 Lipoproteins Interleukins ATP Binding Cassette Transporter, Subfamily B, Member 1 Hepacivirus Neoplasm Proteins Polymorphism, Single Nucleotide Genotype Middle Aged Viral Load Female Male Humans
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[Characterization of Serial Passage of 1b/2a Chimera Hepatitis C Virus Cell Culture System Carrying Envelope E1E2 Coding Gene from Hebei Strain of China].

Bing du xue bao = Chinese journal of virology Nov 1, 2015
To character a novel chimera(1b/2a) hepatitis C virus cell culture (HCVcc) system carrying envelope E1E2 coding gene from Hebei strain of China, chimera HCVcc (cHCVcc) was developed from Huh7.5-CD81 cells after transfection with in vitro transcribed ...
Humans China Hepatitis C Cell Line Viral Envelope Proteins Hepacivirus Serial Passage
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Classification models of HCV NS3 protease inhibitors based on support vector machine (SVM).

Combinatorial chemistry & high throughput screening Jan 1, 2015
Inhibition of the hepatitis C virus (HCV) non-structural protein 3 (NS3) serine protease by molecule inhibitors is an attractive strategy for the treatment of hepatitis C. We built four classification models based on a dataset of 413 HCV NS3 protease...
Protease Inhibitors Databases, Pharmaceutical Humans Quantitative Structure-Activity Relationship Molecular Docking Simulation Viral Nonstructural Proteins Hepacivirus Support Vector Machine Hepatitis C
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