AIMC Topic: Humans

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DEep learning-based rapid Spiral Image REconstruction (DESIRE) for high-resolution spiral first-pass myocardial perfusion imaging.

NMR in biomedicine
The objective of the current study was to develop and evaluate a DEep learning-based rapid Spiral Image REconstruction (DESIRE) technique for high-resolution spiral first-pass myocardial perfusion imaging with whole-heart coverage, to provide fast an...

Novel in Vivo and in Vitro Pharmacokinetic/Pharmacodynamic-Based Human Starting Dose Selection for Glofitamab.

Journal of pharmaceutical sciences
We present a novel approach for first-in-human (FIH) dose selection of the CD20xCD3 bispecific antibody, glofitamab, based on pharmacokinetic/pharmacodynamic (PKPD) assessment in cynomolgus monkeys to select a high, safe starting dose, with cytokine ...

A Framework for Using Real-World Data and Health Outcomes Modeling to Evaluate Machine Learning-Based Risk Prediction Models.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
OBJECTIVES: We propose a framework of health outcomes modeling with dynamic decision making and real-world data (RWD) to evaluate the potential utility of novel risk prediction models in clinical practice. Lung transplant (LTx) referral decisions in ...

Machine learning in systematic reviews: Comparing automated text clustering with Lingo3G and human researcher categorization in a rapid review.

Research synthesis methods
Systematic reviews are resource-intensive. The machine learning tools being developed mostly focus on the study identification process, but tools to assist in analysis and categorization are also needed. One possibility is to use unsupervised automat...

[Use of medical archives for research and patient care].

Der Urologe. Ausg. A
In recent years, technology in healthcare has experienced a dynamic increase, with the collection of data being a central component. In particular, artificial intelligence (AI), such as machine learning and deep learning, makes it possible to perform...

A Case for the Use of Artificial Intelligence in Glaucoma Assessment.

Ophthalmology. Glaucoma
We hypothesize that artificial intelligence (AI) applied to relevant clinical testing in glaucoma has the potential to enhance the ability to detect glaucoma. This premise was discussed at the recent Collaborative Community on Ophthalmic Imaging meet...

Relationship between vedolizumab serum concentrations in the induction phase and early and sustained response in the first year of treatment in patients with ulcerative colitis.

Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria
OBJECTIVE: Evidence on the usefulness of proactive monitoring of vedolizumab serum concentrations during the induction phase of treatment is limited. The objective of our study was to evaluate the effectiveness of measuring such concentrations during...

Risk Assessment and Determination of Factors That Cause the Development of Hyperinsulinemia in School-Age Adolescents.

Medicina (Kaunas, Lithuania)
: Hyperinsulinemia and insulin resistance are not synonymous; if the risk of developing insulin resistance in adolescents is monitored, they do not necessarily have hyperinsulinemia. It is considered a condition of pre-diabetes and represents a condi...

Heart Rate Modeling and Prediction Using Autoregressive Models and Deep Learning.

Sensors (Basel, Switzerland)
Physiological time series are affected by many factors, making them highly nonlinear and nonstationary. As a consequence, heart rate time series are often considered difficult to predict and handle. However, heart rate behavior can indicate underlyin...

Deep Stacking Network for Intrusion Detection.

Sensors (Basel, Switzerland)
Preventing network intrusion is the essential requirement of network security. In recent years, people have conducted a lot of research on network intrusion detection systems. However, with the increasing number of advanced threat attacks, traditiona...