Kidney transplantation remains the optimal treatment for end-stage renal disease, yet persistent organ shortages and inequitable allocation necessitate innovative solutions. Artificial intelligence (AI) and machine learning (ML) have emerged as promi...
BACKGROUND: Delays in organ retrieval following brain death (BD) can compromise organ viability, increasing the risk of post-transplant complications. In 2021, the Transplant Authority of Tamil Nadu, India, implemented an artificial intelligence (AI)...
International journal of health geographics
Apr 28, 2025
BACKGROUND: Illicit kidney trade networks, operating globally, involve intricate interactions among various players, most notably buyers, sellers, brokers, and surgeons. A comprehensive understanding of these trade networks is, however, hindered by t...
Increasing the number of organ donations after circulatory death (DCD) has been identified as one of the most important ways of addressing the ongoing organ shortage. While recent technological advances in organ transplantation have increased their s...
BACKGROUND: An ideal lung allocation system should reduce waiting list deaths, improve transplant survival, and ensure equitable organ allocation. This study aimed to develop a novel lung allocation score (LAS) system, the MaxBenefit LAS, to maximize...
BMC medical informatics and decision making
Feb 24, 2025
BACKGROUND: The principles of urgency, utility, and benefit are fundamental concepts guiding the ethical and practical decision-making process for organ allocation; however, LT allocation still follows an urgency model.
ASAIO journal (American Society for Artificial Internal Organs : 1992)
Mar 29, 2024
In kidney transplantation, pairing recipients with the highest longevity with low-risk allografts to optimize graft-donor survival is a complex challenge. Current risk prediction models exhibit limited discriminative and calibration capabilities and ...
Lesion scores on procurement donor biopsies are commonly used to guide organ utilization for deceased-donor kidneys. However, frozen sections present challenges for histological scoring, leading to inter- and intra-observer variability and inappropri...
BACKGROUND: An emerging strategy to expand the donor pool is the use of a steatotic donor liver (SDLs; ≥ 30% macrosteatosis on biopsy). With the obesity epidemic and prevalence of nonalcoholic fatty liver disease, SDLs have been reported in 59% of al...
Recommended practices that follow match-run sequences for hard-to-place kidneys succumb to many declines, accruing cold ischemic time and exacerbating kidney quality that may lead to unnecessary kidney discard. Hard-to-place deceased donor kidneys ac...
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