BACKGROUND: Intravenous immunoglobulin (IVIG) resistance of Kawasaki disease (KD) patients have a heightened risk of coronary artery lesions. We aimed to explore the predictive factors of IVIG resistance of KD from Shandong Peninsula in China, and es...
Intravenous immunoglobulin (IVIG) has been established as the first-line therapy for Kawasaki disease (KD). However, approximately 10%-20% of pediatric patients exhibit IVIG resistance. Current machine learning (ML) models demonstrate suboptimal pred...
BACKGROUND: Kawasaki disease (KD) is a leading cause of acquired heart disease in children that is treated with intravenous immunoglobulin (IVIG). However, 10-20% of cases exhibit IVIG resistance, which increases the risk of coronary complications. E...
Kawasaki disease (KD) is a common pediatric vasculitis, with coronary artery lesions (CALs) representing its most severe complication. Early identification of high-risk patients, including those with disease resistant to first-line treatments, is ess...
Kawasaki disease (KD) is a leading cause of acquired heart disease in children, often resulting in coronary artery complications such as dilation, aneurysms, and stenosis. While intravenous immunoglobulin (IVIG) is effective in reducing immunologic i...
BACKGROUND AND OBJECTIVE: Intravenous immunoglobulin (IVIG) is a prominent therapeutic agent for Kawasaki disease (KD) that significantly reduces the incidence of coronary artery anomalies. Various methodologies, including machine learning, have been...
BACKGROUND: Approximately 10-20% of Kawasaki disease (KD) patients suffer from intravenous immunoglobulin (IVIG) resistance, placing them at higher risk of developing coronary artery aneurysms. Therefore, we aimed to construct an IVIG resistance pred...
INTRODUCTION: In Kawasaki disease (KD), accurate prediction of intravenous immunoglobulin (IVIG) resistance is crucial to reduce a risk for developing coronary artery lesions.
Kawasaki disease is the leading cause of pediatric acquired heart disease. Coronary artery abnormalities are the main complication of Kawasaki disease. Kawasaki disease patients with intravenous immunoglobulin resistance are at a greater risk of deve...
Therapeutic proteins are exposed to numerous stresses during their manufacture, shipping, storage and administration to patients, causing them to aggregate and form particles through a variety of different mechanisms. These varied mechanisms generate...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.