AIMC Topic: Insulin

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Parental perspectives following the implementation of advanced hybrid closed-loop therapy in children and adolescents with type 1 diabetes and elevated glycaemia.

Diabetic medicine : a journal of the British Diabetic Association
AIMS: To identify from a parental perspective facilitators and barriers of effective implementation of advanced hybrid closed-loop (AHCL) therapy in children and adolescents with type 1 diabetes (T1D) with elevated glycaemia.

Physiological model-based machine learning for classifying patients with binge-eating disorder (BED) from the Oral Glucose Tolerance Test (OGTT) curve.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Binge eating disorder (BED) is the most frequent eating disorder, often confused with obesity, with which it shares several characteristics. Early identification could enable targeted therapeutic interventions. In this study...

Learning control-ready forecasters for Blood Glucose Management.

Computers in biology and medicine
Type 1 diabetes (T1D) presents a significant health challenge, requiring patients to actively manage their blood glucose (BG) levels through regular bolus insulin administration. Automated control solutions based on machine learning (ML) models could...

An automatic deep reinforcement learning bolus calculator for automated insulin delivery systems.

Scientific reports
In hybrid automatic insulin delivery (HAID) systems, meal disturbance is compensated by feedforward control, which requires the announcement of the meal by the patient with type 1 diabetes (DM1) to achieve the desired glycemic control performance. Th...

Which surrogate insulin resistance indices best predict coronary artery disease? A machine learning approach.

Cardiovascular diabetology
BACKGROUND: Various surrogate markers of insulin resistance have been developed, capable of predicting coronary artery disease (CAD) without the need to detect serum insulin. For accurate prediction, they depend only on glucose and lipid profiles, as...

A Scalable Application of Artificial Intelligence-Driven Insulin Titration Program to Transform Type 2 Diabetes Management.

Diabetes technology & therapeutics
Despite new pharmacotherapy, most patients with long-term type 2 diabetes are still hyperglycemic. This could have been solved by insulin with its unlimited potential efficacy, but its dynamic physiology demands frequent titrations which are overdem...

Application of machine learning in affordable and accessible insulin management for type 1 and 2 diabetes: A comprehensive review.

Artificial intelligence in medicine
Proper insulin management is vital for maintaining stable blood sugar levels and preventing complications associated with diabetes. However, the soaring costs of insulin present significant challenges to ensuring affordable management. This paper con...

The association of serum irisin with anthropometric, metabolic, and bone parameters in obese children and adolescents.

Frontiers in endocrinology
BACKGROUND: Irisin is an adipomyokine secreted by muscle and adipose cells, and it plays a role in glucose, fat, and bone metabolism. This study aimed to determine the correlation of serum irisin levels with anthropometric, metabolic, and bone parame...

Time for Using Machine Learning for Dose Guidance in Titration of People With Type 2 Diabetes? A Systematic Review of Basal Insulin Dose Guidance.

Journal of diabetes science and technology
BACKGROUND: Real-world studies of people with type 2 diabetes (T2D) have shown insufficient dose adjustment during basal insulin titration in clinical practice leading to suboptimal treatment. Thus, 60% of people with T2D treated with insulin do not ...

Deep learning fuzzy immersion and invariance control for type-I diabetes.

Computers in biology and medicine
In this study, a novel approach is proposed for glucose regulation in type-I diabetes patients. Unlike most studies, the glucose-insulin metabolism is considered to be uncertain. A new approach on the basis of the Immersion and Invariance (I&I) theor...