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KETOS: Clinical decision support and machine learning as a service - A training and deployment platform based on Docker, OMOP-CDM, and FHIR Web Services.

PloS one
BACKGROUND AND OBJECTIVE: To take full advantage of decision support, machine learning, and patient-level prediction models, it is important that models are not only created, but also deployed in a clinical setting. The KETOS platform demonstrated in...

Enhancing the security of patients' portals and websites by detecting malicious web crawlers using machine learning techniques.

International journal of medical informatics
INTRODUCTION: There is increasing demand for access to medical information via patients' portals. However, one of the challenges towards widespread utilisation of such service is maintaining the security of those portals. Recent reports show an alarm...

Wikidata: A large-scale collaborative ontological medical database.

Journal of biomedical informatics
Created in October 2012, Wikidata is a large-scale, human-readable, machine-readable, multilingual, multidisciplinary, centralized, editable, structured, and linked knowledge-base with an increasing diversity of use cases. Here, we raise awareness of...

[E-health and "Cancer outside the hospital walls", Big Data and artificial intelligence].

Bulletin du cancer
To heal otherwise in oncology has become an imperative of Public Health and an economic imperative in France. Patients can therefore receive live most of their care outside of hospital with more ambulatory care. This ambulatory shift will benefit fro...

Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning.

Nature communications
Highly specific Cas9 nucleases derived from SpCas9 are valuable tools for genome editing, but their wide applications are hampered by a lack of knowledge governing guide RNA (gRNA) activity. Here, we perform a genome-scale screen to measure gRNA acti...

Ontology based mining of pathogen-disease associations from literature.

Journal of biomedical semantics
BACKGROUND: Infectious diseases claim millions of lives especially in the developing countries each year. Identification of causative pathogens accurately and rapidly plays a key role in the success of treatment. To support infectious disease researc...

Automated SNOMED CT concept and attribute relationship detection through a web-based implementation of cTAKES.

Journal of biomedical semantics
BACKGROUND: Information in Electronic Health Records is largely stored as unstructured free text. Natural language processing (NLP), or Medical Language Processing (MLP) in medicine, aims at extracting structured information from free text, and is le...

What do patients learn about psychotropic medications on the web? A natural language processing study.

Journal of affective disorders
BACKGROUND: Low rates of medication adherence remain a major challenge across psychiatry. In part, this likely reflects patient concerns about safety and adverse effects, accurate or otherwise. We therefore sought to characterize online information a...

Machine learning application for prediction of locoregional recurrences in early oral tongue cancer: a Web-based prognostic tool.

Virchows Archiv : an international journal of pathology
Estimation of risk of recurrence in early-stage oral tongue squamous cell carcinoma (OTSCC) remains a challenge in the field of head and neck oncology. We examined the use of artificial neural networks (ANNs) to predict recurrences in early-stage OTS...

Siamese Neural Networks for User Identity Linkage Through Web Browsing.

IEEE transactions on neural networks and learning systems
Linking online identities of users among countless heterogeneous network services on the Internet can provide an explicit digital representation of users, which can benefit both research and industry. In recent years, user identity linkage (UIL) thro...