AIMC Topic: Knowledge Bases
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A NICE perspective on computable biomedical knowledge.
BMJ health & care informatics
Jul 1, 2020
INTRODUCTION: The National Institute for Health and Care Excellence (NICE) plays a central role in the NHS. We distill knowledge of best practice from the best available sources of evidence and share this across the health and care system, typically ...
Decision support for Scotland's health and social care: learning from an outcomes-focused approach.
BMJ health & care informatics
Jul 1, 2020
This short report shares learning from the research and development phase of the national decision support programme in NHS Scotland. It outlines how the programme has adopted an outcomes-focused approach which has guided critical decisions on soluti...
Does not compute: challenges and solutions in managing computable biomedical knowledge.
BMJ health & care informatics
Jul 1, 2020
Computers can potentially play a key role in resolving knowledge mobilisation bottlenecks in health and care through decision support at the point of care based on computable biomedical knowledge (CBK). But the management of CBK comes with a range of...
HDR UK supporting mobilising computable biomedical knowledge in the UK.
BMJ health & care informatics
Jul 1, 2020
Computable biomedical knowledge (CBK) represents an evolving area of health informatics, with potential for rapid translational patient benefit. Health Data Research UK (HDR UK) is the national Institute for Health Data Science, whose aim is to unite...
Collaborative, Multidisciplinary Evaluation of Cancer Variants Through Virtual Molecular Tumor Boards Informs Local Clinical Practices.
JCO clinical cancer informatics
Jul 1, 2020
PURPOSE: The cancer research community is constantly evolving to better understand tumor biology, disease etiology, risk stratification, and pathways to novel treatments. Yet the clinical cancer genomics field has been hindered by redundant efforts t...
GlyGen data model and processing workflow.
Bioinformatics (Oxford, England)
Jun 1, 2020
SUMMARY: Glycoinformatics plays a major role in glycobiology research, and the development of a comprehensive glycoinformatics knowledgebase is critical. This application note describes the GlyGen data model, processing workflow and the data access i...
Analysis of knowledge bases and research hotspots of coronavirus from the perspective of mapping knowledge domain.
Medicine
May 29, 2020
BACKGROUND: Coronaviruses have drawn attention since the beginning of the 21st century. Over the past 17 years, coronaviruses have triggered several outbreaks of epidemic in people, which brought great threats to global public health security. We ana...
iDISK: the integrated DIetary Supplements Knowledge base.
Journal of the American Medical Informatics Association : JAMIA
Apr 1, 2020
OBJECTIVE: To build a knowledge base of dietary supplement (DS) information, called the integrated DIetary Supplement Knowledge base (iDISK), which integrates and standardizes DS-related information from 4 existing resources.
Formal axioms in biomedical ontologies improve analysis and interpretation of associated data.
Bioinformatics (Oxford, England)
Apr 1, 2020
MOTIVATION: Over the past years, significant resources have been invested into formalizing biomedical ontologies. Formal axioms in ontologies have been developed and used to detect and ensure ontology consistency, find unsatisfiable classes, improve ...
OncoMX: A Knowledgebase for Exploring Cancer Biomarkers in the Context of Related Cancer and Healthy Data.
JCO clinical cancer informatics
Mar 1, 2020
PURPOSE: The purpose of OncoMX knowledgebase development was to integrate cancer biomarker and relevant data types into a meta-portal, enabling the research of cancer biomarkers side by side with other pertinent multidimensional data types.
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