AIMC Topic: Large Language Models

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Designing diverse and high-performance proteins with a large language model in the loop.

PLoS computational biology
We present a protein engineering approach to directed evolution with machine learning that integrates a new semi-supervised neural network fitness prediction model, Seq2Fitness, and an innovative optimization algorithm, biphasic annealing for diverse...

Large language models for the screening step in systematic reviews in dentistry.

Journal of dentistry
OBJECTIVES: This study assessed the performance of chatbots in the screening step of a systematic review (SR) with an exemplary focus on tooth segmentation on dental radiographs using artificial intelligence (AI).

Clinical Management of Wasp Stings Using Large Language Models: Cross-Sectional Evaluation Study.

Journal of medical Internet research
BACKGROUND: Wasp stings are a significant public health concern in many parts of the world, particularly in tropical and subtropical regions. The venom of wasps contains a variety of bioactive compounds that can lead to a wide range of clinical effec...

Evaluating the capacity of large language models to interpret emotions in images.

PloS one
The integration of artificial intelligence, specifically large language models (LLMs), in emotional stimulus selection and validation offers a promising avenue for enhancing emotion comprehension frameworks. Traditional methods in this domain are oft...

Enhancing the Accuracy of Human Phenotype Ontology Identification: Comparative Evaluation of Multimodal Large Language Models.

Journal of medical Internet research
BACKGROUND: Identifying Human Phenotype Ontology (HPO) terms is crucial for diagnosing and managing rare diseases. However, clinicians, especially junior physicians, often face challenges due to the complexity of describing patient phenotypes accurat...

Early detection of occupational stress: Enhancing workplace safety with machine learning and large language models.

PloS one
Occupational stress is a major concern for employers and organizations as it compromises decision-making and overall safety of workers. Studies indicate that work-stress contributes to severe mental strain, increased accident rates, and in extreme ca...

MedBLIP: A multimodal method of medical question-answering based on fine-tuning large language model.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Medical visual question answering is crucial for effectively interpreting medical images containing clinically relevant information. This study proposes a method called MedBLIP (Medical Treatment Bootstrapping Language-Image Pretraining) to tackle vi...

Large Language Models in Medicine: Applications, Challenges, and Future Directions.

International journal of medical sciences
In recent years, large language models (LLMs) represented by GPT-4 have developed rapidly and performed well in various natural language processing tasks, showing great potential and transformative impact. The medical field, due to its vast data info...

Evaluating performance of large language models for atrial fibrillation management using different prompting strategies and languages.

Scientific reports
This study evaluated large language models (LLMs) using 30 questions, each derived from a recommendation in the 2024 European Society of Cardiology (ESC) guidelines for atrial fibrillation (AF) management. These recommendations were stratified by cla...