Reactive oxygen species are produced by a number of stimuli and can lead both to irreversible intracellular damage and signaling through reversible post-translational modification. It is unclear which factors contribute to the sensitivity of cysteine...
This study aimed to identify the predictive capacity of wellness questionnaires on measures of training load using machine learning methods. The distributions of, and dose-response between, wellness and other load measures were also examined, offerin...
Reproductive toxicity endpoints are a significant safety concern in the assessment of the adverse effects of chemicals in drug discovery. Computational models that can accurately predict a chemical's toxic potential are increasingly pursued to replac...
In coeliac disease (CeD), immune-mediated small intestinal damage is precipitated by gluten, leading to variable symptoms and complications, occasionally including aggressive T-cell lymphoma. Diagnosis, based primarily on histopathological examinatio...
Magnetic resonance imaging (MRI) systems and their continuous, failure-free operation is crucial for high-quality diagnostics and seamless workflows. One important hardware component is coils as they detect the magnetic signal. Before every MRI scan,...
BMC medical informatics and decision making
Jan 6, 2021
BACKGROUND: Next-generation sequencing provides comprehensive information about individuals' genetic makeup and is commonplace in oncology clinical practice. However, the utility of genetic information in the clinical decision-making process has not ...
BACKGROUND: Circular RNA (circRNA) is a novel type of RNA with a closed-loop structure. Increasing numbers of circRNAs are being identified in plants and animals, and recent studies have shown that circRNAs play an important role in gene regulation. ...
BACKGROUND: Effectively identifying patients with COVID-19 using nonpolymerase chain reaction biomedical data is critical for achieving optimal clinical outcomes. Currently, there is a lack of comprehensive understanding in various biomedical feature...
BACKGROUND: Social media plays a critical role in health communications, especially during global health emergencies such as the current COVID-19 pandemic. However, there is a lack of a universal analytical framework to extract, quantify, and compare...
Computational and mathematical methods in medicine
Jan 6, 2021
Identification of bacterial type III secreted effectors (T3SEs) has become a popular research topic in the field of bioinformatics due to its crucial role in understanding host-pathogen interaction and developing better therapeutic targets against th...
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