In this study, we propose a conceptual framework of decision support tools, built upon machine learning and multi-objective optimization, aimed at offering a deeper understanding of the complex trade-offs involved in hematopoietic stem cell transplan...
Coughing behavior is associated with conditions such as sleep apnea, asthma, and chronic obstructive pulmonary disorder and can severely affect quality of life in those affected. In this context, coughing quantification is often important, but routin...
Quantitative T1 and T2 mapping is a useful tool to assess properties of healthy and diseased tissues. However, clinical diagnostic imaging remains dominated by relaxation-weighted imaging without direct collection of relaxation maps. Dedicated resear...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Jun 1, 2025
AIM: The use of artificial intelligence (AI) and machine learning (ML) is increasingly widespread in radiation oncology. However, patient engagement to date has been poor. Respect for persons in the healthcare setting and the principle of informed co...
Parkinson's disease (PD) is characterised by a complex array of motor, psychiatric, and gastrointestinal symptoms, many of which are linked to disruptions in neuroactive metabolites. Dysregulated activity of tryptophan 2,3-dioxygenase (TDO), a key en...
This study aimed to identify key predictors of self-perceptions of aging (SPA) among older adults by examining a comprehensive set of potential predictors across physical, psychological, social, and demographic domains. Data from over 4000 American a...
Our study investigated the predictive efficacy of AI-based Machine Learning (ML) model for determining HER2 status in a population of 3424 breast cancer patients. Multivariate logistic regression analysis identified several independent variables that...
Journal of the American Medical Informatics Association : JAMIA
Jun 1, 2025
OBJECTIVE: To develop a continual process for linking more comprehensive external mortality data to electronic health records (EHRs) for a large healthcare system, which can serve as a template for other healthcare systems.
BACKGROUND: Pre-eclampsia (PE) contributes to more than one-fourth of all maternal deaths and half a million newborn deaths worldwide every year. Early screening and interventions can reduce PE incidence and related complications. We aim to 1) tempor...
The relationship between Superparamagnetic Iron Oxide Nanoparticles (SPIONs) surface chemistry and their toxicological outcomes is crucial for biomedical applications, including drug delivery and imaging diagnostics. SPIONs' surface properties-such a...
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