PURPOSE: To provide an overview of fundamental concepts in machine learning (ML), review the literature on ML applications in imaging analysis of pituitary tumors for the last 10 years, and highlight the future directions on potential applications of...
Electro- and magneto-encephalography are functional neuroimaging modalities characterised by their ability to quantify dynamic spatiotemporal activity within the brain. However, the visualisation techniques used to illustrate these effects are curren...
Automatic multi-classification of breast cancer histopathological images has remained one of the top-priority research areas in the field of biomedical informatics, due to the great clinical significance of multi-classification in providing diagnosis...
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
Jun 1, 2020
BACKGROUND: Deep learning (DL) has demonstrated human expert levels of performance for medical image classification in a wide array of medical fields, including ophthalmology. In this article, we present the results of our DL system designed to deter...
PURPOSE: To identify optimal machine learning methods for radiomics-based differentiation of local recurrence versus inflammation from post-treatment nasopharyngeal positron emission tomography/X-ray computed tomography (PET/CT) images.
Integrative biology : quantitative biosciences from nano to macro
May 21, 2020
Characterization of decision-making in cells in response to received signals is of importance for understanding how cell fate is determined. The problem becomes multi-faceted and complex when we consider cellular heterogeneity and dynamics of biochem...
The increasing use of CRISPR-Cas9 in medicine, agriculture, and synthetic biology has accelerated the drive to discover new CRISPR-Cas inhibitors as potential mechanisms of control for gene editing applications. Many anti-CRISPRs have been found that...
With the explosive growth of biological sequences generated in the post-genomic era, one of the most challenging problems in bioinformatics and computational biology is to computationally characterize sequences, structures and functions in an efficie...
Biologists very often use enrichment methods based on statistical hypothesis tests to identify gene properties that are significantly over-represented in a given set of genes of interest, by comparison with a 'background' set of genes. These enrichme...
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